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Three-Dimensional Imaging of Tight Junction Network Across Multiple Layers of Human Epidermis by Array Tomography Using Backscattered Electron-Mode Scanning Electron Microscopy

research LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy

August 2019 in “Journal of Investigative Dermatology”

The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.

research Immunolocalization of junctional proteins in human hairs indicates that the membrane complex stabilizes the inner root sheath while desmosomes contact the companion layer through specific keratins

12 citations , January 2013 in “Acta Histochemica”

Junctional proteins stabilize the inner root sheath and connect the companion layer in human hair.

research Single Root hair growth under constant force: insights into wall mechanics

October 2025 in “bioRxiv (Cold Spring Harbor Laboratory)”

Root hair growth slows under force, confirming a model of cell wall mechanics.

Magnetic Hairstyling: Engineering Human Hair Surfaces with Polyelectrolyte-Stabilized Magnetite Nanoparticles

research Magnetic coiffure: Engineering of human hair surfaces with polyelectrolyte-stabilised magnetite nanoparticles

1 citations , August 2022 in “Chemical engineering journal advances”

Scientists made human hair magnetic by coating it with special nanoparticles.

research The importance of the neuro‐immuno‐cutaneous system on human skin equivalent design

73 citations , August 2019 in “Cell Proliferation”

Human skin models are essential for studying skin's sensory, immune, and nervous system interactions.

research A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

15 citations , June 2019 in “eLife”

Activin A and follistatin control when hair cells develop in mouse ears.

research Immunohistochemical Localization of Basement Membrane Components During Hair Follicle Morphogenesis

59 citations , March 1984 in “Journal of Investigative Dermatology”

research Neuroendocrine Controls of Keratin Expression in Human Skin

December 2018 in “IntechOpen eBooks”

Neurohormones help control skin health and could treat skin disorders.

research Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models

4 citations , January 2014 in “BioMed Research International”

Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.

Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

August 2023 in “International Journal of Molecular Sciences”

The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.

research Involvement of mechanical stress in androgenetic alopecia

10 citations , January 2015 in “International Journal of Trichology”

Mechanical stress contributes to hair loss in androgenetic alopecia.

research Nevoid basal cell carcinoma syndrome. Some histologic observations on the cutaneous lesions

3 citations , March 1966 in “Archives of Dermatology”

Nevoid basal cell carcinomas start in the skin's top layer and hair follicles.

research Use of hair pores to determine the orientation of collagen fibers in skin

6 citations , April 2001 in “The Anatomical Record”

A new method using hair pores can help align skin grafts better, improving results.

research The Role of Mast Cells in Skin Aging: Mechanisms and Therapeutic Advances

1 citations , October 2025 in “Experimental Dermatology”

Mast cells influence skin aging and are potential targets for anti-aging treatments.

Oxytocin Receptor Expression in Hair Follicle Stem Cells: A Promising Model for Biological and Therapeutic Discovery in Neuropsychiatric Disorders

research OXYTOCIN RECEPTOR EXPRESSION IN HAIR FOLLICLE STEM CELLS: A PROMISING MODEL FOR BIOLOGICAL AND THERAPEUTIC DISCOVERY IN NEUROPSYCHIATRIC DISORDERS

October 2023 in “IBRO neuroscience reports”

Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.

Identification of Transcriptional Targets of Wnt/β-Catenin Signaling in Dermal Papilla Cells of Human Scalp Hair Follicles: EP2 Is a Novel Transcriptional Target of Wnt3a

research Identification of transcriptional targets of Wnt/β-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3a

29 citations , March 2010 in “Journal of Dermatological Science”

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

research [A longitudinal elasticity study of hair from the human head in forensic medicine].

January 1998 in “PubMed”

The method effectively measures hair elasticity and could be useful in forensics.

Label Retaining Cells with Myoepithelial Characteristics from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

36 citations , September 2013 in “PLoS ONE”

Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.

research Surface Engineered Metal-Organic Frameworks (MOFs) Based Novel Hybrid Systems for Effective Wound Healing: A Review of Recent Developments

55 citations , September 2020 in “Frontiers in Bioengineering and Biotechnology”

Engineered MOFs show promise for better wound healing but need more research for human use.

research Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells

31 citations , December 1991 in “Annals of the New York Academy of Sciences”

ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.

research Faculty Opinions recommendation of The keratins of the human beard hair medulla: the riddle in the middle.

March 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Beard hair medulla cells have a unique and varied keratin pattern.

research Reconstructed Tissue-engineered Skin with ES Cell-derived Epidermal Stem Cells and Collagen Sponge

January 2006 in “Journal of Sun Yat-sen University”

Engineered skin using stem cells and collagen sponge effectively healed and regenerated complex skin features in mice.

Computational Design and Development of a Novel Voltammetric Sensor for Minoxidil Detection Based on Electropolymerized Molecularly Imprinted Polymer

research Computational design and development of a novel voltammetric sensor for minoxidil detection based on electropolymerized molecularly imprinted polymer

39 citations , January 2015 in “Journal of Electroanalytical Chemistry”

New sensor detects minoxidil accurately and effectively.

research Selective Elimination of NG2-Expressing Hair Follicle Stem Cells Exacerbates the Sensitization Phase of Contact Dermatitis in a Transgenic Rat Model

2 citations , September 2020 in “International Journal of Molecular Sciences”

Removing certain hair follicle stem cells worsens skin reactions to allergens.

research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

July 2023

The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.

Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-Epithelization and Epidermal Growth

research Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-epithelization and Epidermal Growth

19 citations , June 2008 in “Journal of Investigative Dermatology”

HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.

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Research

research LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy

research Immunolocalization of junctional proteins in human hairs indicates that the membrane complex stabilizes the inner root sheath while desmosomes contact the companion layer through specific keratins

research Single Root hair growth under constant force: insights into wall mechanics

research Magnetic coiffure: Engineering of human hair surfaces with polyelectrolyte-stabilised magnetite nanoparticles

research The importance of the neuro‐immuno‐cutaneous system on human skin equivalent design

research A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea

research Immunohistochemical Localization of Basement Membrane Components During Hair Follicle Morphogenesis

research Neuroendocrine Controls of Keratin Expression in Human Skin

research Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models

research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

research Involvement of mechanical stress in androgenetic alopecia

research Nevoid basal cell carcinoma syndrome. Some histologic observations on the cutaneous lesions

research Use of hair pores to determine the orientation of collagen fibers in skin

research The Role of Mast Cells in Skin Aging: Mechanisms and Therapeutic Advances

research OXYTOCIN RECEPTOR EXPRESSION IN HAIR FOLLICLE STEM CELLS: A PROMISING MODEL FOR BIOLOGICAL AND THERAPEUTIC DISCOVERY IN NEUROPSYCHIATRIC DISORDERS

research Identification of transcriptional targets of Wnt/β-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3a

research [A longitudinal elasticity study of hair from the human head in forensic medicine].

research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland

research Surface Engineered Metal-Organic Frameworks (MOFs) Based Novel Hybrid Systems for Effective Wound Healing: A Review of Recent Developments

research Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells

research Faculty Opinions recommendation of The keratins of the human beard hair medulla: the riddle in the middle.

research Reconstructed Tissue-engineered Skin with ES Cell-derived Epidermal Stem Cells and Collagen Sponge

research Computational design and development of a novel voltammetric sensor for minoxidil detection based on electropolymerized molecularly imprinted polymer

research The Localization of Label-Retaining Cells in Eccrine Glands

research Cell observation method under near-living conditions by scanning electron microscopy

research Characterization of new stem/progenitor cells in skin appendages

research Mediator 1 ablation induces enamel-to-hair lineage conversion through enhancer dynamics

research Selective Elimination of NG2-Expressing Hair Follicle Stem Cells Exacerbates the Sensitization Phase of Contact Dermatitis in a Transgenic Rat Model

research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity

research Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-epithelization and Epidermal Growth