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,
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,
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,
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,
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,
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,
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,
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,
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93 citations
,
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,
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,
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87 citations
,
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research Acne
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,
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,
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73 citations
,
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,
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65 citations
,
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,
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,
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,
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61 citations
,
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61 citations
,
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59 citations
,
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59 citations
,
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,
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54 citations
,
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,
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50 citations
,
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50 citations
,
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49 citations
,
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