375 citations
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June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
338 citations
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July 2009 in “Development” Sox2-positive cells determine specific hair follicle types in mammals.
161 citations
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August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
90 citations
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August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
85 citations
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June 2017 in “Journal of Investigative Dermatology” Blimp1 is crucial for hair follicle growth and skin health.
81 citations
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February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
67 citations
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September 2017 in “Cell Reports” Caloric restriction improves skin and fur structure but can cause muscle loss and movement issues.
53 citations
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July 2016 in “Cosmetics” Future hair cosmetics will be safer and more effective.
46 citations
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March 2011 in “Science Advances” 3D bioprinting can now create skin with hair-like structures for medical use.
42 citations
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December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
41 citations
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January 2018 in “Advances in experimental medicine and biology” 39 citations
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March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
35 citations
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January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
33 citations
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August 2008 in “American Journal Of Pathology” Hedgehog signaling is essential for normal sebaceous gland development and affects keratin 6a expression.
30 citations
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February 2023 in “Animals” Hair follicle traits at 6 months can help select cashmere goats for breeding.
29 citations
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October 2010 in “Journal of Investigative Dermatology” Activating Kras in mouse skin causes excess skin and hair loss.
26 citations
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May 2016 in “Journal of biological chemistry/The Journal of biological chemistry” sPLA2-IIE is crucial for normal hair follicle structure and skin health.
22 citations
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March 2021 in “Materials Today Bio” Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
22 citations
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August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
22 citations
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June 2020 in “iScience” Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
21 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
21 citations
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January 2020 in “Conservation Physiology” Hair follicles increase hair cortisol levels, so consistent hair collection methods are important.
17 citations
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May 2025 in “MedComm” Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
17 citations
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September 2020 in “Inflammation and Regeneration” WNT activation in scalp fibroblasts boosts hair growth by increasing FGF9.
16 citations
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November 2022 in “eLife” Both gene and non-gene areas of DNA evolved to make some mammals hairless.
16 citations
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May 2015 in “Tissue Engineering Part C-methods” A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
15 citations
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February 2006 in “Journal of Investigative Dermatology” More research is needed to understand and treat cicatricial alopecias.
11 citations
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October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
11 citations
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June 2017 in “Asian-Australasian journal of animal sciences” Fox genes are important for hair growth and development in cashmere goats.
11 citations
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March 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.