240 citations
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April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
231 citations
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October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
210 citations
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May 2006 in “The FASEB journal” Oxidative stress causes hair to gray by damaging and killing pigment cells.
175 citations
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January 1995 in “Birkhäuser Basel eBooks” Human hair growth and structure are influenced by keratin proteins, genes, melanin, and lipids.
161 citations
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June 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair stops producing melanin as it transitions from the growth phase to the resting phase.
138 citations
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June 2023 in “Molecules” Skin pigmentation varies due to genetics, UV exposure, and drugs, with treatments available but requiring medical advice.
132 citations
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September 2009 in “Experimental Dermatology” A reliable system was developed to distinguish hair growth stages, aiding in identifying hair growth promoters or inhibitors.
115 citations
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August 2008 in “The Journal of Clinical Endocrinology & Metabolism” Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.
106 citations
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June 2005 in “Journal of Investigative Dermatology” The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
94 citations
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April 2018 in “Nature Genetics” New genetic locations explain much of hair color variation in Europeans.
93 citations
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October 2006 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
86 citations
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August 2000 in “Pigment cell research” Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.
82 citations
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May 2005 in “Dermatologic therapy” Laser hair removal has advanced to effectively reduce hair for various skin types and hair colors.
81 citations
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October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
75 citations
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January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
75 citations
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March 1998 in “Journal of Investigative Dermatology” The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
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March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
62 citations
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October 2017 in “JAMA facial plastic surgery” Condensed nanofat with fat grafts effectively improves atrophic facial scars.
62 citations
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December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
60 citations
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January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying a specific inhibitor lightens skin and hair color.
60 citations
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February 1997 in “Journal of Dermatological Science” Liposomes can safely and effectively deliver substances to mouse hair follicles, potentially useful for human hair treatments.
58 citations
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February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
58 citations
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November 2013 in “Journal of Innovative Optical Health Sciences” Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
57 citations
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February 1994 in “Experimental dermatology” Melatonin affects mouse skin and may regulate skin functions.
56 citations
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November 1958 in “The Journal of Cell Biology” A unique skin cell similar to hair bulb melanocytes was identified, with better preservation using permanganate fixation.
56 citations
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November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
55 citations
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December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
53 citations
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September 2011 Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.
47 citations
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June 1996 in “International Journal of Legal Medicine” Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
45 citations
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October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.