15 citations
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January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
2 citations
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May 2023 in “Photobiomodulation, photomedicine, and laser surgery” Light therapy is effective and safe for treating skin color disorders like vitiligo and dark spots.
January 2026 in “Molecules” Dihydroartemisinin could be a versatile cosmetic ingredient but needs more research and development.
October 2025 in “Cell Transplantation” New hair loss treatments like stem cells and gene therapy show promise but need more research for safety and effectiveness.
11 citations
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January 2016 in “Evidence-based Complementary and Alternative Medicine” Rice bran extract can increase melanin production and may help treat melanin deficiency.
4 citations
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July 2019 in “Clinics in Dermatology” The document concludes that while white skin, nail, and mucosa diseases increase skin cancer risk, they are generally harmless, especially compared to darker pigmentation conditions.
38 citations
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June 2005 in “Acta Biochimica Polonica” Splenic eumelanin in C57BL/6 mice is different from hair eumelanin.
130 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
46 citations
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August 2022 in “Animals” miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.
4 citations
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February 2025 in “Pharmaceuticals” Voglibose may help treat skin hyperpigmentation safely.
January 2025 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Green tea compound EGCG may help hair growth by boosting cell activity.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
148 citations
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September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.
138 citations
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June 2023 in “Molecules” Skin pigmentation varies due to genetics, UV exposure, and drugs, with treatments available but requiring medical advice.
31 citations
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April 2019 in “Journal of Cutaneous Pathology” Hair becomes gray and thin as we age, and while most hair loss in older people is due to genetics, there's a chance for gray hair to regain color under certain conditions.
15 citations
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April 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” A3B5 can reduce skin pigmentation and slow melanoma growth.
12 citations
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May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
4 citations
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May 2022 in “International journal of molecular sciences” Heat-killed Enterococcus faecalis EF-2001 may promote hair growth and transition hair follicles to the growth phase.
3 citations
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September 2023 in “Stem Cell Research & Therapy” Stem cells can be used to create long-lasting skin cells for treating pigment disorders.
July 2023 in “Biomolecules” The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.
15 citations
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June 2021 in “International Journal of Molecular Sciences” CMC2.24 and CMC2.23 reduce melanin safely and effectively.
41 citations
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July 2016 in “Journal of Investigative Dermatology” Dysplastic nevi have unique gene expressions, making them distinct from common melanocytic nevi.
41 citations
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December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
December 2025 in “Biomolecules” Targeting protein S-palmitoylation could lead to new skin disease treatments.
Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.
3 citations
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December 2023 in “Biomedicines” PRP therapy helps skin heal and improve by promoting cell growth and repair.
1 citations
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July 2025 in “Frontiers in Veterinary Science” Tibetan sheep have specific genes for high-altitude adaptation and wool traits, aiding breeding strategies.
March 2024 in “International journal of molecular sciences” Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.
189 citations
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July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
106 citations
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January 2013 in “Clinical and Developmental Immunology” Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.