research Targeting IGF1 ‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging
Reducing IGF-1 can help rejuvenate hair follicles and prevent hair graying and loss.
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research Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
research Premature Graying of Hair: A Comprehensive Review and Recent Insights
Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.
research Corticotropin releasing hormone and the skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Incorporation of hair follicles in 3D bioprinted models of human skin
3D bioprinting can now create skin with hair-like structures for medical use.
research Targeting the Hippo/YAP /TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research The Potential Reversible Transition between Stem Cells and Transient-Amplifying Cells: The Limbal Epithelial Stem Cell Perspective
Corneal cells can potentially revert to stem cells, aiding in repair and regeneration.
research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research Zebrafish Model of Hereditary Pigmentary Disorders
Zebrafish help understand genetic causes of skin pigment disorders like albinism.
research The Dickkopf Protein Family in Non-Neoplastic Disorders: Emerging Roles and Therapeutic Targeting
DKK proteins could help diagnose and treat various non-cancerous diseases.
research The Effects of Spermidine on Functional and Transcriptomic Markers in Human Primary Keratinocytes
Spermidine may improve skin health and hair growth by enhancing cell function.
research Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin
Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
research Mineralocorticoid Receptor Antagonists—A New Sprinkle of Salt and Youth
MR antagonists may improve skin health and wound healing, especially in aging.
research Epidermal stem cells: skin surveillance and clinical perspective
Epidermal stem cells are vital for skin healing and have potential for treating skin disorders.
research The Dark Side of Gefitinib: Reflectance Confocal Microscopy Applied to Hair Hyperpigmentation
Gefitinib can cause hair and eyebrow darkening.
research Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity
Quiescent adult stem cells are crucial for tissue repair and maintenance.
research A Comprehensive Review of Mammalian Pigmentation: Paving the Way for Innovative Hair Colour-Changing Cosmetics
Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
research Cell death in skin function, inflammation, and disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research Skin tissue engineering
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research Store-operated calcium channels in skin
Calcium channels are vital for normal skin function and their dysfunction can lead to skin issues.
research Drug Repurposing of Voglibose, a Diabetes Medication for Skin Health
Voglibose may help treat skin hyperpigmentation safely.
research Unraveling the Molecular Mechanism of Bider Marking Formation in Dun Mongolian Horses Through Transcriptome Sequencing
"Bider" markings in Dun Mongolian horses are caused by a complex network of genes and pathways.
research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
research Mettl3-catalyzed m 6 A regulates histone modifier and modification expression in self-renewing somatic tissue
Mettl3 is essential for normal tissue development and self-renewal by regulating gene expression.
research N1-acetylspermidine is a determinant of hair follicle stem cell fate
N1-acetylspermidine promotes hair follicle stem cell self-renewal.
research Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
research Zinc and Zinc Transporters in Dermatology
Zinc is crucial for skin health and treating various skin disorders.
research The Roles of WNT Signaling Pathways in Skin Development and Mechanical-Stretch-Induced Skin Regeneration
WNT signaling is crucial for skin development and healing.
research The Endocrine Function of the Skin: An Analytical Narrative
The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.