research Proceedings of the Heinz Maurer-Symposium “Review and Preview in Science for Healthy Skin” June 28th 2014, Jakobsberg, Boppard, Germany
The symposium concluded that environmental factors significantly contribute to skin aging.
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research Tribuloside acts on the PDE/cAMP/PKA pathway to enhance melanogenesis, melanocyte dendricity and melanosome transport
Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
research Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata
Regenerative therapies show promise for treating vitiligo and alopecia areata.
research Efficacy of an agonist ofα-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation
Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management
Restoring hair bulb immune privilege is crucial for managing alopecia areata.
research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis
ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
research Repigmentation of Gray Hair After Thyroid Hormone Treatment
Gray hair regained color after thyroid hormone treatment.
research Hearing impairment in patients with alopecia areata
Alopecia areata may lead to hearing loss.
research Eph/ephrin signaling in epidermal differentiation and disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research Wound Healing Mechanisms
Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
research Live imaging of skin immunity using two-photon microscopy: a short review
Two-photon microscopy improves skin imaging but faces safety and cost challenges for clinical use.
research Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research Extracellular Caspase-1 induces hair stem cell migration in wounded and inflamed skin conditions
Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.
research Vitiligo - Part 2 - classification, histopathology and treatment
New vitiligo treatments focus on controlling immune damage and restoring skin color.
research Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C
Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
research Classic versus non‐classic: A survival Kit for life in the skin
Melanocytes in different body areas have evolved to perform specific functions based on their location.
research Narrow-Band Ultraviolet B Phototherapy in Vitiligo
NB-UVB phototherapy is an effective and safe treatment for vitiligo, especially on hands and feet, and can be improved with tacrolimus.
research Transgneic Endothelin 3 Regulates Murine Pigment Production and Coat Color
The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.
research Hair Follicle Pigmentation
Hair color is determined by melanin produced and transferred in hair follicles.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research Restoration of skin pigmentation after deep partial or full-thickness burn injury
The review suggests that there are various treatments to help restore skin color after severe burns.
research Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice
Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.
research Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences
Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
research Natural Compound Isoliensinine Inhibits Stress-Induced Hair Greying by Blocking β2-Adrenoceptor
Isoliensinine, a natural compound, prevents stress-related hair greying by blocking a specific receptor on hair cells.
research Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons
Hair-follicle stem cells can become neurons.
research Anatomy and Physiology of the Skin
The skin is essential for protection, temperature control, and immune defense.
research Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses
Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.
research Three Streams for the Mechanism of Hair Graying
Hair graying may be caused by stem cell depletion from stress or melanocyte damage.