57 citations
,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
18 citations
,
August 2021 in “PLoS ONE” Melanocyte progenitor cells are found in human fat tissue and can become mature melanocytes, which may help treat skin issues.
3 citations
,
December 2024 in “Stem Cell Reports” Low fucosylation boosts stem cell growth in the eye.
101 citations
,
April 2013 in “Science” Feather pigment patterns form through melanocyte arrangement and simple regulatory mechanisms.
8 citations
,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
44 citations
,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of early-stage melanocytes is reduced in vitiligo-affected skin, which may explain treatment resistance.
13 citations
,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
January 2004 in “Giornale di Metafisica: revista bimestrale di filosofia” Increased Wnt signaling causes hair graying by depleting melanocyte stem cells in aged mice.
April 2016 in “Journal of Investigative Dermatology” The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
13 citations
,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
6 citations
,
November 2013 in “International Journal of Radiation Biology” Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
1 citations
,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
1 citations
,
January 2018 in “Methods in molecular biology” The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
45 citations
,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
86 citations
,
February 2012 in “Journal of Clinical Investigation” Stem cells in hair follicles are diverse and change throughout the hair cycle.
1 citations
,
January 2016 in “Elsevier eBooks” The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
November 2013 in “Institutional Repositories DataBase (IRDB)” Gamma-ray exposure during hair rest phase harms hair growth and color in mice.
February 2011 in “Expert Review of Dermatology” Researchers found potential new targets for treating melanoma and nonmelanoma skin cancers, and identified a possible cause and treatment for male pattern baldness and eczema.
5 citations
,
March 2019 in “Scientific Reports” The technique can isolate cells to help treat skin pigmentation issues.
April 2018 in “Journal of Investigative Dermatology” BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
April 2023 in “Dermatology practical & conceptual” Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
260 citations
,
June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
149 citations
,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
91 citations
,
March 2011 in “Stem Cell Reviews and Reports” Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
66 citations
,
March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
January 2006 in “Yearbook of Dermatology and Dermatologic Surgery” Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
41 citations
,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.