17 citations
,
June 2017 in “British Journal of Dermatology” The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
17 citations
,
December 2014 in “Cell Stem Cell” Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.
3 citations
,
January 2019 in “Advances in stem cells and their niches” Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
3 citations
,
October 2011 in “JAT. Journal of applied toxicology/Journal of applied toxicology” Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.
March 2021 in “Research Society and Development” A blue Staffordshire Bull Terrier had hair loss due to color dilution alopecia, confirmed by tests, but no treatment was pursued.
June 2025 in “British Journal of Dermatology” Melanocytic matricoma can look like skin cancer but is usually harmless; surgery and follow-up are advised.
January 2006 in “Yearbook of Dermatology and Dermatologic Surgery” Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
41 citations
,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
1 citations
,
June 2025 in “Journal of Cellular and Molecular Medicine” Plant-derived compounds may help reverse grey hair by boosting melanin production.
46 citations
,
April 2014 in “PLOS ONE” Gray hair may be caused by lower antioxidant activity in hair cells.
3 citations
,
May 1979 in “PubMed”
April 2026 in “npj Regenerative Medicine” Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
7 citations
,
February 2019 in “International Journal of Dermatology” Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.
47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
Hair turning darker can be a sign of skin cancer.
1 citations
,
January 2012 in “Human health handbooks” Hair color is determined by melanin types and gene activity.
January 2024 in “International Research Journal Of Modernization In Engineering Technology And Science” Hair growth serums reduce hair fall and improve growth with mostly positive reviews.
January 2004 in “Linchuang pifuke zazhi” Black hairs have more pigment-related genes, while gray hairs have more keratin-related genes.
1 citations
,
June 2011 in “InTech eBooks” Darker skin provides more protection against UV damage and cancer.
July 2025 in “Pigment International” Follicular vitiligo causes hair to gray without skin color loss.
August 2023 in “Journal of Investigative Dermatology” 7 citations
,
March 1990 in “Pigment Cell Research” Certain chemicals cause hair graying in black mice but not yellow mice.
12 citations
,
May 2019 in “Journal of cosmetic dermatology” Effective treatments for premature hair graying still require significant research.
15 citations
,
January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
October 2025 in “Molecular Genetics and Genomics” 26 citations
,
January 2018 in “Annals of dermatology/Annals of Dermatology” Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
5 citations
,
February 2022 in “Frontiers in physiology” Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
140 citations
,
August 2010 in “Pigment Cell & Melanoma Research” We know a lot about mouse hair color, but not much about human hair color differences.
1066 citations
,
March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.