37 citations
,
July 2002 in “Archives of Pathology & Laboratory Medicine” Tyrosinase and gp100 proteins can help diagnose and treat melanoma.
34 citations
,
July 2011 in “Journal of the European Academy of Dermatology and Venereology” The study concluded that scalp tumors show different patterns based on age, gender, and tumor thickness, and emphasized the importance of early detection and scalp examinations.
30 citations
,
September 2009 in “Seminars in Cutaneous Medicine and Surgery” Dermoscopy has greatly improved the diagnosis of skin lesions and our understanding of their morphology and biology.
24 citations
,
January 2023 in “Cancer Research” AMPK activation may reduce melanoma risk in red-haired individuals.
21 citations
,
February 2013 in “Clinics in Dermatology” New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.
14 citations
,
September 2020 in “Journal of the American Academy of Dermatology” Electrical impedance spectroscopy improves biopsy accuracy and efficiency for skin lesions.
4 citations
,
November 2022 in “British Journal of Cancer” Men with melanoma have a higher risk of later being diagnosed with prostate cancer.
December 2019 in “Medicina estética” Dermoscopy is underused in aesthetic medicine, but it increases diagnosis confidence; more training is needed.
December 2019 in “Medicina estética” Dermoscopy is underused in aesthetic medicine, but it increases diagnostic confidence, and professionals need more training.
May 2019 in “Australasian Journal of Dermatology” New insights in skin conditions show a complex link between certain moles and melanoma, improved hair loss treatments, and the need to identify different types of lupus.
April 2016 in “JAMA Dermatology” Acne is not a key diagnostic feature for PCOS, postadolescent men with acne may have insulin resistance, melanoma patients often have few moles, tumor size in CSCC indicates higher risk of serious outcomes, and hidradenitis suppurativa is linked to higher risk of heart problems and death.
7 citations
,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
3 citations
,
October 2018 in “Journal of Mind and Medical Sciences” Biological therapy boosts the immune system to effectively fight melanoma.
2 citations
,
August 2013 in “Journal of Investigative Dermatology” Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
October 2019 in “European Journal of Dermatology” The boy's hair and skin color differences are due to a pigmentation disorder.
August 2023 in “Journal of Investigative Dermatology”
2 citations
,
January 2002 Melanin and melanocytes contribute to the brown pigmentation in stasis dermatitis.
1 citations
,
July 2018 in “JAMA dermatology” Poliosis causes white hair patches due to lack of melanin.
October 2025 in “Molecular Genetics and Genomics”
August 2018 in “Pediatric Dermatology” A baby had a unique skin condition with a pale patch and surrounding dark hairs, not linked to other health issues.
35 citations
,
July 2007 in “Dermatologic clinics” Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.
Hair turning darker can be a sign of skin cancer.
4 citations
,
July 2019 in “Clinics in Dermatology” The document concludes that while white skin, nail, and mucosa diseases increase skin cancer risk, they are generally harmless, especially compared to darker pigmentation conditions.
6 citations
,
September 2010 in “Pigment Cell & Melanoma Research” We know less about human hair pigmentation than mouse coat color, but pH and cysteine levels are key factors.
93 citations
,
October 2006 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
4 citations
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March 2020 in “JAAD Case Reports” Vitamin B12 deficiency can cause darkening of all nails.
140 citations
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August 2010 in “Pigment Cell & Melanoma Research” We know a lot about mouse hair color, but not much about human hair color differences.
3 citations
,
March 2021 in “Cureus” A rare combination of halo nevi, nonsegmental vitiligo, and early gray hair can occur together.
June 2025 in “British Journal of Dermatology” Melanocytic matricoma can look like skin cancer but is usually harmless; surgery and follow-up are advised.
2 citations
,
August 2025 in “Reports — Medical Cases Images and Videos” A rare pigmented skin tumor called melanotrichoblastoma was diagnosed in a 51-year-old woman.