46 citations
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March 2019 in “Journal of Pineal Research” Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.
January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.
April 2023 in “Australasian Journal of Dermatology” Lentiginous melanoma is most common on the face, especially the nose, cheek, and pre-auricular areas, with men more likely to have it on the scalp, ears, upper back, and trapezius, and women on the cheek and anterior arm. Sun damage is a key factor in its formation.
October 2024 in “Journal of the Pakistan Medical Association” Genetics, nutrition, lifestyle, and hormones affect early grey hair, but more research is needed.
3 citations
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January 2005 in “Photochemistry and Photobiology” Protein kinase C epsilon may promote skin cancer development after UV exposure by affecting nearby cells.
August 2018 in “Journal of The American Academy of Dermatology” Regular follow-up visits, especially with dermatologists, can lower death rates for melanoma patients, with socioeconomic factors also affecting outcomes.
A man's scalp hair loss was due to a combined melanocytic nevus and alopecia areata, suggesting a possible link between the two conditions.
January 2025 in “Frontiers in Medicine” Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.
14 citations
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March 2017 in “Genes and immunity” Certain microRNAs may help treat alopecia areata by targeting immune pathways.
June 2006 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” Melatonin may help reduce the needed dose of prednisolone and improve hair growth in alopecia areata patients.
2 citations
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August 1987 in “Archives of Dermatology” Langerhans' cells are not responsible for depigmentation in this mouse model.
March 2026 in “Biomolecules” MicroRNAs play a key role in controlling hair growth and quality in sheep and goats.
101 citations
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July 1998 in “Journal of Investigative Dermatology” UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
Melampus might have cured Proetus' daughters, who possibly had ergotism or Cushing's syndrome, using the herb Helleborus niger, but a mix of factors could have caused their symptoms.
39 citations
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April 2019 in “The journal of immunology/The Journal of immunology” Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
June 2021 in “Asian Journal of Medical Sciences” Vitamin B12 deficiency can cause reversible skin darkening.
11 citations
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August 1987 in “Archives of Dermatology” Langerhans' cells are not involved in hair depigmentation in these mice.
1 citations
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November 2025 in “Science Advances” Two gene variants cause white spots in cattle.
14 citations
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October 2017 in “Gene Expression Patterns” A new mouse model helps study melanocyte cells using GFP expression.
6 citations
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November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Gene expression, especially Dkk4, is key to cat color patterns.
467 citations
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May 1999 in “Molecular Cell” Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.
Melatonin reduces BMP2 gene expression in goat hair follicles during the resting period.
29 citations
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June 2005 in “Journal of Zoo and Wildlife Medicine” Most hair loss in captive rhesus macaques is likely due to environmental and behavioral factors.
January 2022 in “Figshare” Melatonin affects when and how certain genes work during the different stages of hair growth in goats.
92 citations
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September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
Loss of Dnmt3a and Dnmt3b leads to more aggressive skin tumors, but blocking PPAR-γ can reduce this effect.
January 2024 in “Grail of science” Premature hair graying is caused by various factors and mechanisms.
February 2026 in “Case Reports in Dermatology” Finasteride can cause melasma, especially in people with darker skin.
June 2009 in “Pigment Cell & Melanoma Research” Preventing hair graying may be possible by managing oxidative stress and activating melanocyte stem cells.
Cialis and Finasteride could be repurposed to treat aggressive melanoma.