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The Effects of Synthetic and Natural Hormones of the Adrenal Cortex on Melanin Deposition in Adrenalectomized Black Rats Fed Diets Adequate and Deficient in Vitamin B1

research THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

27 citations , October 1945 in “Endocrinology”

Synthetic hormone treatment reduces melanin and hair growth in rats.

[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs

research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs

26 citations , July 2007 in “Biochemical Pharmacology”

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

research Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin

25 citations , June 2015 in “Clinical, Cosmetic and Investigational Dermatology”

Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.

research Circulating testosterone and feather-gene expression of receptors and metabolic enzymes in relation to melanin-based colouration in the barn owl

14 citations , September 2017 in “General and comparative endocrinology”

Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.

research Extradermal melanin transfer? Lack of macroscopic spleen melanization in old C57BL/6 mice with de-synchronized hair cycle.

10 citations , June 2009 in “Acta Biochimica Polonica”

Old C57BL/6 mice with unsynchronized hair cycles show less melanin in their spleens.

research Photo‐protective effect of cuttlefish ink melanin on human hair

7 citations , September 2021 in “Journal of Applied Polymer Science”

Cuttlefish ink melanin protects hair from UV damage.

research Field melanin mapping of the hairless scalp

7 citations , November 2011 in “Skin Research and Technology”

The study found a specific pattern of uneven melanin distribution on balding scalps that could help understand skin diseases caused by light exposure.

research Melanin Light Absorption as the Necessary but Not Sufficient Condition for Photoepilation: Miniaturization and Eclipse Phenomena

4 citations , March 2013 in “The American Journal of Cosmetic Surgery”

Melanin absorbing light is necessary but not enough for effective hair removal by light treatment.

research Raman investigation of in vivo radiation exposure on melanin in murine hair

2 citations , March 2025 in “PNAS Nexus”

Raman spectroscopy can detect radiation exposure in mouse hair with high accuracy for up to 7 days.

research Mitigation of epidermal growth factor receptor inhibitor-induced side effects utilizing melanin and vascular-specific lasers: A case report series

1 citations , May 2017 in “Journal of cosmetic and laser therapy”

Lasers can help reduce skin side effects from cancer treatment.

Marine Biomass Derived Melanin Chitosan Composites as Natural Black Hair Colorants: Charge Reversal and Electrostatic Deposition Mechanism

research Marine-Biomass-Derived Melanin–Chitosan Composites as Natural Black Hair Colorants: Charge Reversal and Electrostatic Deposition Mechanism

June 2026 in “Organics”

A natural hair dye from cuttlefish ink and chitosan effectively colors hair black without harmful chemicals.

The Development of Squid Ink Melanin Nanoparticles as a Multifunctional Colorant Anchored on Hair Fibers: Preparation, Physicochemical Characterization and Dyeing Performance

research The Development of Squid Ink Melanin Nanoparticles as a Multifunctional Colorant Anchored on Hair Fibers: Preparation, Physicochemical Characterization and Dyeing Performance

April 2026 in “Biomolecules”

Squid ink melanin nanoparticles create a safe, long-lasting black hair dye that protects hair and offers UV protection.

research In Vivo Non-Invasive Observation of Dynamic Changes in Hair Shaft, Melanin, and Collagen During the C57BL/6 Follicle Cycle

September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)”

Non-invasive methods can effectively monitor hair growth cycles, aiding hair loss treatment development.

research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin

April 2024 in “International journal of molecular sciences”

Dermal factors are crucial in regulating melanin production in skin.

research An introduction to skin disease in melanin rich skin

March 2021

Melanin-rich skin has unique challenges in diagnosing and treating skin diseases.

research 적하수오 에탄올 추출물의 melanin 합성 촉진효과

April 2017 in “생명과학회지”

PMEE may help reverse greying hair by boosting melanin production.

Alopecia Areata and Medical Modulation of the Intrinsic Property of Melanin to Transform Light Into Chemical Energy Through Water Dissociation

research Alopecia Areata and Medical Modulation of the Intrinsic Property of Melanin to Transform Light Into Chemical Energy Through the Water Dissociation

January 2017 in “Archives of clinical and biomedical research”

Enhancing melanin's energy generation may help treat alopecia areata.

research 686 Topical melatonin unfolds differential anti-aging effects in human skin by inhibiting mTORC1 activity via TSC2 stimulation

July 2024 in “Journal of Investigative Dermatology”

Topical melatonin may reduce skin aging by inhibiting certain cellular pathways.

research Reproductive performance of hair ewes and rams implanted with melatonin previous to the anestrus season in northwest Mexico

April 2023 in “Tropical Animal Health and Production”

Giving melatonin to sheep before the non-breeding season can improve their chances of reproducing in northwest Mexico.

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Research

research THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs

research Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin

research Circulating testosterone and feather-gene expression of receptors and metabolic enzymes in relation to melanin-based colouration in the barn owl

research Extradermal melanin transfer? Lack of macroscopic spleen melanization in old C57BL/6 mice with de-synchronized hair cycle.

research Photo‐protective effect of cuttlefish ink melanin on human hair

research Field melanin mapping of the hairless scalp

research Melanin Light Absorption as the Necessary but Not Sufficient Condition for Photoepilation: Miniaturization and Eclipse Phenomena

research Raman investigation of in vivo radiation exposure on melanin in murine hair

research Mitigation of epidermal growth factor receptor inhibitor-induced side effects utilizing melanin and vascular-specific lasers: A case report series

research Marine-Biomass-Derived Melanin–Chitosan Composites as Natural Black Hair Colorants: Charge Reversal and Electrostatic Deposition Mechanism

research The Development of Squid Ink Melanin Nanoparticles as a Multifunctional Colorant Anchored on Hair Fibers: Preparation, Physicochemical Characterization and Dyeing Performance

research In Vivo Non-Invasive Observation of Dynamic Changes in Hair Shaft, Melanin, and Collagen During the C57BL/6 Follicle Cycle

research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin

research An introduction to skin disease in melanin rich skin

research 적하수오 에탄올 추출물의 melanin 합성 촉진효과

research Alopecia Areata and Medical Modulation of the Intrinsic Property of Melanin to Transform Light Into Chemical Energy Through the Water Dissociation

research 686 Topical melatonin unfolds differential anti-aging effects in human skin by inhibiting mTORC1 activity via TSC2 stimulation

research Reproductive performance of hair ewes and rams implanted with melatonin previous to the anestrus season in northwest Mexico

research Exogenous Melatonin Promotes Expression Differences of Skin Hair Follicles Related Genes in Cashmere Goat

research Topical application of synthetic melanin promotes tissue repair

research Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis

research Freeze‐Drying Tumor Tissues Derived Bio‐Patches With Hair Melanin Nanoparticles Integration for Wound Healing

research Activity evaluation of epidermo-melanin unit and dermal damage in melasma

research Einfluss von Melatonin auf die Physiologie des Haares

research Regulation of melanin synthesis in goat hair follicles by melatonin through the Wnt/β-catenin pathway

research The effect of melatonin treatment on hair follicle cycle in angora rabbits

research A preliminary study of markers for human hair follicle melanin stem cell

research Quantitative mapping of melanin in hair fibers using fluorescence lifetime imaging microscopy

research 568 Novel synthetic melanin nanoparticles improve skin wound healing