research Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069.
LGD1069 effectively prevents breast tumors in mice without toxicity.
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840-870 / 1000+ resultsresearch Phosphatidylinositol 3-Kinase/Akt-Dependent and -Independent Protection Against Apoptosis in Normal Human Melanocytes
Normal human melanocytes can avoid cell death through multiple pathways.
research Differences in cell subsets between sun-exposed and unexposed skin: preliminary single-cell sequencing and biological analysis from a single case
Sun-exposed skin shows different cell activity and gene expression, suggesting targets to prevent skin aging and cancer.
research 144 Deciphering the role of the hexosamine pathway in skin homeostasis
The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.
research A computationally inferred regulatory heart aging model including post-transcriptional regulations
Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
research Microcirculation-Promoting Effect of Escin on Cutaneous Tissue via Gsk3β Down-Regulation
Escin improves skin blood flow and health by enhancing blood vessel networks.
research Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling
Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.
research Reply
Dr. Jorizzo questions the long-term benefits of minoxidil and tretinoin, while Dr. Olsen defends their effectiveness and stresses the need for public education on these treatments.
research Antioxidant and Antibacterial Activity of Organic Extracts of Roots of <i>Glycyrrhiza Glabra Linn</i>
The organic extracts from the roots of Glycyrrhiza Glabra Linn have antioxidant and antibacterial properties.
research Human hair melanins: what we have learned and have not learned from mouse coat color pigmentation
We know less about human hair pigmentation than mouse coat color, but pH and cysteine levels are key factors.
research Finasteride Inhibits Melanogenesis throughthe Regulation of Melanocortin 1 Receptorin Melanocytes
Finasteride reduces melanin production in skin cells.
research Hibiscus rosa sinensis L. anthocyanins prevent lipid peroxidation and improve antioxidant status in the liver of streptozotocin-induced diabetic rats
Hibiscus anthocyanins help protect the liver and improve antioxidants in diabetic rats.
research Il-10 family members as novel responders to genotoxic stress
IL-19 and IL-24 help cells respond to DNA damage and could be targeted for cancer and age-related disease treatments.
research Additional file 2 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus
Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.
research A Retrospective Study on the Safety of Systemic Minoxidil for Hair Loss in the Older Population
Systemic minoxidil is generally safe for older adults, but caution is needed for those with heart risks.
research 687 BMP signaling in the hair follicle stem cell niche regulates hair growth and skin pigmentation
BMP signaling controls hair growth and skin color.
research Transcranial photobiomodulation for brain diseases: review of animal and human studies including mechanisms and emerging trends
Light therapy on the brain shows promise for treating brain diseases and improving brain function.
research The effect of melatonin treatment on hair follicle activity in growing chinchillas
Melatonin boosts hair growth in chinchillas.
research Ni–Cu BimetallicNanozyme and Minoxidil Co-LoadedDissolving Microneedles Reshape Hair Follicle Microenvironment forAndrogenic Alopecia Treatment
A new treatment using dissolvable microneedles with nickel-copper and minoxidil improves hair growth and health in androgenic alopecia.
research Effects of Gonadal Steroids on Melanocytes in Developing Hamsters
Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
research 皮膚組織の再生に向けた皮膚由来幹細胞に関する研究
Skin-derived stem cells could help treat skin aging and pigmentation issues.
research 1298 External light activates hair follicle stem cells through eyes via the ipRGC-SCN-sympathetic neural circuit
Light can activate hair growth through a pathway from the eyes to hair follicles.
research Additional file 5 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus
Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.
research A case of patchy alopecia areata sparing lesional greying hairs
Greying hairs may be protected from alopecia areata.
research Enhancing Quercetin Bioavailability Attenuates Aging Phenotypes via the Gut Microbiota–Intestinal Barrier Axis in Aged Mice
Bioavailable quercetin may help improve aging signs by positively affecting gut health.
research Primary Involvement of NADPH Oxidase 4 in Hypoxia-Induced Generation of Reactive Oxygen Species in Adipose-Derived Stem Cells
NADPH oxidase 4 is key for stem cell activity and growth under low oxygen.
research Evaluating the Causal Relationship Between Human Blood Metabolites and the Susceptibility to Alopecia Areata
Blood metabolites significantly influence alopecia areata risk.
research Endothelium-Derived Relaxing Factor and Minoxidil: Active Mechanisms in Hair Growth
Minoxidil may promote hair growth by mimicking a natural body chemical.
research New frontiers in human hair follicle (neuro‐)endocrinology
Human scalp hair follicles can produce and respond to several hormones, affecting hair growth and pigmentation.
research Molecular Basis of Maintaining Circannual Rhythm in the Skin of Cashmere Goat
Goat skin adapts to seasonal changes through genes that respond to daylight length, affecting hormone levels and potentially making skin cells light-sensitive.