60 citations
,
February 2015 in “Biomaterials” A surface with VEGF can specifically capture endothelial cells from flowing fluids.
56 citations
,
November 2022 in “Biomolecules” Targeting macrophages may improve wound healing.
55 citations
,
April 2022 in “Frontiers in Immunology” Cholesterol affects coronavirus spread and could be a target for treatment.
55 citations
,
March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
51 citations
,
March 2022 in “Frontiers in Immunology” Alarmin cytokines are key in controlling skin immunity and inflammation.
51 citations
,
December 2017 in “Skin Appendage Disorders” Stress may trigger hair loss by affecting immune protection in hair follicles.
50 citations
,
April 2021 in “Frontiers in Immunology” New therapies targeting skin neuroimmune interactions could treat neuropathic pain.
49 citations
,
December 2022 in “Pharmacological Reviews” Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.
46 citations
,
May 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Significant progress was made in understanding PXE, but effective treatments are still needed.
46 citations
,
August 2006 in “Mechanisms of Development” Runx1 is crucial for proper hair structure and development.
45 citations
,
August 2018 in “Haematologica” Macrophage iron release is crucial for hair growth and wound healing.
45 citations
,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
44 citations
,
January 2023 in “New Phytologist” FER and TOR signaling help root hair growth in low temperature and low nitrate conditions.
44 citations
,
April 2021 in “Frontiers in Cell and Developmental Biology” MSC-derived exosomes may help in skin repair and regeneration.
43 citations
,
May 1999 in “Journal of Biological Chemistry” Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
42 citations
,
April 2021 in “Pharmaceuticals” Five FDA-approved drugs may help block COVID-19 virus entry.
42 citations
,
June 2019 in “Aging” 3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.
40 citations
,
November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
39 citations
,
June 2023 in “Advanced Materials” Microneedles offer a promising, painless, and efficient way to deliver vaccines and therapies directly to the skin.
39 citations
,
August 2017 in “Annual Review of Genetics” Understanding tissue regeneration in animals can improve regenerative medicine.
37 citations
,
July 2002 in “Archives of Pathology & Laboratory Medicine” Tyrosinase and gp100 proteins can help diagnose and treat melanoma.
36 citations
,
December 2021 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.
34 citations
,
February 2015 in “Frontiers in Cellular Neuroscience” Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
33 citations
,
December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
32 citations
,
August 2024 in “Journal of Investigative Dermatology” In vitro skin models are improving but still need more innovation to fully replicate human skin.
29 citations
,
April 2019 in “Acta neuropathologica communications” Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
28 citations
,
September 2020 in “International Journal of Molecular Sciences” Leucocyte-rich platelet-rich plasma boosts cell activity and helps wound healing.
28 citations
,
November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
26 citations
,
January 2025 in “iScience” PRP helps tissue repair but lacks standard preparation methods.
26 citations
,
September 2023 in “Journal of Allergy and Clinical Immunology” Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.