January 2026 in “PubMed Central” The document explores the formation, construction, and performance of self-assembled nanoparticles (SANs) from natural products, highlighting their improved drug absorption and distribution capabilities. These nanoscale assemblies are created through non-covalent interactions using techniques like nanoprecipitation and emulsion-solvent evaporation, resulting in superior physicochemical properties and drug release performance. However, challenges such as stability and large-scale industrial application persist. Future research should aim to enhance production methods, stability, and investigate their use in targeted and responsive drug delivery systems.
April 2023 in “Chinese Medical Journal” Human hair follicle stem cells help repair tendon injuries.
Mechanical stress causes ligament thickening through WISP-1 and Hedgehog signaling.
1 citations
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January 2012 in “Springer eBooks” Mesotherapy can cause serious side effects like infections and skin reactions.
202 citations
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August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
7 citations
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March 1986 in “British Veterinary Journal” Canine skin has two main layers: the epidermis and dermis, with a supportive subcutis layer.
11 citations
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January 2018 in “IET Nanobiotechnology” The scaffolds significantly sped up wound healing in dogs and were safe.
2 citations
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June 2001 in “Medical Electron Microscopy” Trichilemmal cysts may form from hair follicle outer root sheath growth.
4 citations
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August 1999 in “Clinical Cosmetic and Investigational Dermatology” 29 citations
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December 2021 in “Biomedicines” Exosomes from different stem cell sources affect immune cells and brain cell growth differently.
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
July 2024 in “Journal of Investigative Dermatology” Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.
December 2023 in “Modern engineering and innovative technologies” 101 citations
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April 2013 in “Science” Feather pigment patterns form through melanocyte arrangement and simple regulatory mechanisms.
July 2024 in “Journal of Investigative Dermatology” The new skin organoid system effectively mimics human skin for studying its functions, injuries, and diseases.
January 2002 in “中国人民解放军军医大学学报：英文版” 
8 citations
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January 2021 in “Smart materials in medicine” The new hydrogel is good for wound dressing because it absorbs water quickly, has high porosity, can release drugs, fights bacteria, and helps wounds heal with less scarring.
39 citations
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February 2024 in “Small” Microneedles are becoming essential tools in medicine for sensing, drug delivery, and communication.
Exosomes from fat-derived stem cells help repair large bone defects by attracting and enhancing bone marrow stem cells.
December 2019 in “Ukrainian Journal of Veterinary and Agricultural Sciences” Donkey and horse hair have different microscopic structures, which can help tell them apart.
100 citations
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May 2006 in “American Journal Of Pathology” Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
February 2026 in “Human Cell” MSC-CM can boost skin cell growth and movement, aiding skin repair.
1 citations
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September 2023 in “ACS Biomaterials Science & Engineering” Human hair keratin hydrogels show promise for use in regenerative medicine.
355 citations
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August 2013 in “Acta Biomaterialia” The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.
37 citations
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December 2018 in “Frontiers in Immunology” Biodegradable microparticles help wounds heal without scars.
3 citations
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February 2015 in “Mechanisms of development” Hormones and stretching both needed for nipple area skin growth in mice.
1 citations
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March 1998 in “Journal of Dermatological Science” April 2018 in “Dermatologic Surgery” 8 citations
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January 2025 in “Cell Transplantation” MSC-derived EVs show promise for therapy, but production and understanding need improvement.
37 citations
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February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.