April 2018 in “Journal of Investigative Dermatology” Hair follicle stem cells can change their role to ensure proper hair development.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
May 2017 in “American Society of Health-System Pharmacists eBooks”
September 2008 in “Fertility and Sterility” Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
397 citations
,
February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
245 citations
,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
237 citations
,
January 2010 in “The Journal of Sexual Medicine” The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.
222 citations
,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
169 citations
,
May 2006 in “Genes & Development” Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.
165 citations
,
January 2014 in “Dermatology Research and Practice” Zinc is effective for treating various skin conditions, including warts and acne.
57 citations
,
December 2021 in “Nature Communications” Non-canonical Wnt signaling helps intestinal stem cells move to injury sites for tissue repair.
49 citations
,
January 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
32 citations
,
February 2024 in “Growth Hormone & IGF Research” Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
21 citations
,
August 2014 in “Gynecological Endocrinology” Higher hs-CRP levels in Indian adolescent women with PCOS are more related to BMI than PCOS itself.
19 citations
,
November 2012 in “Journal of Dermatological Treatment” Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.
18 citations
,
February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
16 citations
,
January 2006 in “The Aging Male” Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
12 citations
,
April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
9 citations
,
February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.
8 citations
,
June 2012 in “PloS one” Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
4 citations
,
October 2007 in “Dermatologic Clinics” Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
2 citations
,
January 2025 in “Cutis” Glycemic control medications for Type 2 diabetes can affect skin conditions like psoriasis.
1 citations
,
January 2023 in “Portuguese Journal of Dermatology and Venereology” JAK inhibitors effectively treat skin conditions and topical forms are safer.
1 citations
,
January 2009 in “Elsevier eBooks” Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.
November 2025 in “Cancer Management and Research” Targeting Keratin 17 may help overcome cancer therapy resistance.
June 2006 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” Melatonin may help reduce the needed dose of prednisolone and improve hair growth in alopecia areata patients.
20 citations
,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
14 citations
,
March 2018 in “Translational Stroke Research” Finasteride helps protect brain in old male rats.
3 citations
,
September 2020 Dyclonine can effectively reduce skin issues by inhibiting the TRPV3 channel.