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GlossaryMetabolic Changes

alterations in body's chemical processes affecting energy and substance production

Metabolic changes refer to alterations in the body's chemical processes that convert food into energy and other necessary substances. These changes can be influenced by factors such as diet, exercise, hormones, and diseases, and they can impact overall health, including weight, energy levels, and even hair growth. For professionals, understanding these changes is crucial for diagnosing and managing conditions like diabetes, thyroid disorders, and metabolic syndrome.

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Characterization of Metabolic Changes in the Phenotypes of Women with Polycystic Ovary Syndrome in a Large Mediterranean Population from Sicily

research Characterization of metabolic changes in the phenotypes of women with polycystic ovary syndrome in a large Mediterranean population from Sicily

18 citations , July 2019 in “Clinical Endocrinology”

Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.

research Metabolic and hormonal changes during the molt of captive gray seals (Halichoerus grypus)

51 citations , May 1996 in “American journal of physiology. Regulatory, integrative and comparative physiology/American journal of physiology. Regulatory, integrative, and comparative physiology”

Gray seals use more energy and have higher hormone levels during their annual fur-shedding period.

research Changes of metabolic profile in men treated for androgenetic alopecia with 1 mg finasteride

24 citations , January 2010 in “Endocrine Regulations”

Taking 1mg of finasteride daily can mildly improve metabolic health and glucose regulation in men with male pattern baldness.

research Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with the polycystic ovary syndrome.

202 citations , January 1989 in “Journal of Clinical Investigation”

Insulin changes sex hormone levels in women with polycystic ovary syndrome without affecting other hormone releases.

research Cyclic Changes in the Metabolism of Estradiol by Rat Skin During the Hair Cycle**From the Departments of Dermatology and Biochemistry. University of Miami School of Medicine. Miami, Florida, 33136.

17 citations , August 1971 in “Journal of Investigative Dermatology”

research Changes in Metabolic Profile in the Women with a History of PCOS—A Long-Term Follow-Up Study

7 citations , October 2020 in “Journal of Clinical Medicine”

Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.

research Investigating metabolic syndrome markers and body mass index changes in patients with acne vulgaris treated with isotretinoin: A prospective study

7 citations , August 2024 in “Journal of Cosmetic Dermatology”

Isotretinoin effectively treats acne with low risk if dosed correctly.

research Caloric Restriction Promotes Structural and Metabolic Changes in the Skin

67 citations , September 2017 in “Cell Reports”

Caloric restriction improves skin and fur structure but can cause muscle loss and movement issues.

research P25: Assessing the clinicophenotypic characteristics and metabolic changes in males with early‐onset androgenetic alopecia and altered hormonal profile: a comparative cross‐sectional study

July 2022 in “British Journal of Dermatology”

research BH02 (P25): Assessing the clinicophenotypic characteristics and metabolic changes in males with early‐onset androgenetic alopecia and altered hormonal profile: a comparative cross‐sectional study

July 2022 in “British Journal of Dermatology”

Dendrobium Officinale Polysaccharide Improves Hair Regrowth in Androgenetic Alopecia Mice and Is Associated with Coordinated Changes in Local Steroid Metabolism, ESR1 Activation, and Keratin-Related Follicular Responses

research Dendrobium officinale polysaccharide improves hair regrowth in androgenetic alopecia mice and is associated with coordinated changes in local steroid metabolism, ESR1 activation, and keratin-related follicular responses

May 2026 in “Frontiers in Pharmacology”

Dendrobium officinale polysaccharide helps hair regrowth in hair loss mice by affecting local steroid metabolism and hair follicle responses.

Dermatologic Manifestations in Patients with Polycystic Ovary Syndrome: Their Prevalence and Assessment in Relation to Hormonal and Metabolic Changes

research Dermatologic manifestations in patients with polycystic ovary syndrome: their prevalence and assessment in relation to hormonal and metabolic changes

November 2020 in “ALEXMED ePosters (Online)”

People with PCOS often have skin problems like excessive hair growth, hair loss, acne, and dark patches, which are linked to hormonal and metabolic imbalances.

research Cell fate decisions: emerging roles for metabolic signals and cell morphology

100 citations , November 2017 in “EMBO Reports”

Metabolic signals and cell shape influence how cells develop and change.

research Guadalupe fur seal alopecia: a metabolic syndrome associated to climatic anomalies?

1 citations , April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Climate-related nutritional stress may cause hair loss in juvenile male Guadalupe fur seals.

research Physiological dermatological changes during pregnancy: literature review

March 2026 in “International Journal of Health Science”

Pregnancy causes temporary skin changes that are usually harmless.

research Anais Congresso Nacional Sobre Obesidade e Síndrome Metabólica

August 2025 in “Scire Salutis”

Obesity can cause acne in kids and teens due to hormonal and metabolic changes.

research Physiopathology of polycystic ovary syndrome in endocrinology, metabolism and inflammation

70 citations , February 2025 in “Journal of Ovarian Research”

PCOS involves hormonal imbalance, cysts, and ovulation issues, affecting health and increasing disease risks.

Metabolic Syndrome – A New Definition and Management Guidelines: A Joint Position Paper by Various Polish Medical Societies

research Metabolic syndrome – a new definition and management guidelines A joint position paper by the Polish Society of Hypertension, Polish Society for the Treatment of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of Family Medicine, Polish Society of Lifestyle Medicine, Division of Prevention and Epidemiology Polish Cardiac Society, “Club 30” Polish Cardiac Society, and Division of Metabolic and Bariatric Surgery Society of Polish Surgeons

20 citations , August 2022 in “Archives of Medical Science”

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

research Hair loss due to pollution, micro metabolic dysfunction, epigenetics and role of nutrients

September 2024 in “Brazilian Journal of Hair Health”

Nutrients can help improve hair growth and thickness caused by pollution.

research Changes in the PCOS phenotype with age

62 citations , April 2013 in “Steroids”

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

research Severe metabolic disorders coexisting with Werner syndrome: a case report

6 citations , October 2020 in “Endocrine journal”

A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.

research Telogen Effluvium and Metabolic Stress in Modern Weight Loss Interventions: A Narrative Clinical Review

October 2025 in “Brazilian Journal of Hair Health”

Hair loss from weight-loss treatments is usually temporary and reversible.

research Serum lipidomic changes and sex differences in androgenetic alopecia

February 2024 in “Heliyon”

People with androgenetic alopecia have different lipid levels in their blood, which vary between men and women, and may be linked to a higher risk of metabolic syndrome.

research Changes in the serum metabolomics of polycystic ovary syndrome before and after compound oral contraceptive treatment

3 citations , June 2024 in “Frontiers in Endocrinology”

COC treatment improves hormone and metabolic levels in PCOS patients.

Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation

research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation

37 citations , June 2011 in “Journal of Cellular Biochemistry”

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.