July 2017 in “Cardiologia Croatica” Metabolic syndrome's individual issues are real and need treatment to reduce diabetes and heart disease risks.
December 2022 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” Androgenic alopecia in men is mainly linked to family history, hormonal imbalances, and metabolic issues, but can also be influenced by lifestyle habits, environmental factors, and deficiencies in certain vitamins and microelements like copper.
January 2020 in “Archives of urology” Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
Many women with postadolescent acne also have hormonal imbalances and are at higher risk for metabolic issues.
24 citations
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April 2016 in “Experimental Dermatology” Chemical treatments like dyeing, perming, and bleaching damage hair by altering amino acids and lipids.
20 citations
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June 2024 in “Journal of Autoimmunity” Inflammation in rheumatoid arthritis increases steroid activation in cells, reducing inflammation.
11 citations
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January 1976 in “International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine” X-irradiation reduces collagen in rat skin, causing delayed skin damage.
1 citations
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January 2021 in “Prague medical report” Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.
April 2023 in “Journal of Investigative Dermatology” Defective T cell metabolism can cause early skin aging and poor hair follicle stem cell function.
June 2015 in “Obstetrics, gynaecology and reproductive medicine” Hirsutism, excessive hair growth in women, is often caused by polycystic ovarian syndrome and is treated by targeting the cause, lifestyle changes, and medication.
January 2013 in “Российский журнал кожных и венерических болезней” Androgenic alopecia, a common hair loss condition, is linked to changes in androgen metabolism and genetics, and can be treated with finasteride and minoxidil, but these treatments are only fully effective in 10% of patients.
13 citations
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December 2020 in “BMJ Open Diabetes Research & Care” Changes in SHBG levels don't predict diabetes risk reduction.
2 citations
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September 2024 in “Animal Cells and Systems” Hepatitis B virus alters steroid hormones in male mice, reducing dihydrotestosterone to inhibit viral replication.
128 citations
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December 2006 in “Journal of Biological Chemistry” Altering SSAT affects fat metabolism and body fat in mice.
28 citations
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March 2020 in “Journal of ethnopharmacology” Ginsenoside Rb1 slows down aging in mice by affecting cell growth, cell death, and metabolism.
24 citations
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July 2018 in “Stem cells” Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
24 citations
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April 2008 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
22 citations
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September 2011 in “Journal of Investigative Dermatology” TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
17 citations
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May 2012 in “Clinical Endocrinology” Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.
10 citations
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December 2015 in “Clinics in Dermatology” Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.
1 citations
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December 2024 in “Journal of Clinical Medicine” Lower baseline prolactin levels may lead to better insulin resistance improvement with metformin in PCOS patients.
Antioxidant therapy, especially with selenium, can improve skin aging in patients with Metabolic Syndrome.
32 citations
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August 1985 in “Clinical endocrinology” Spironolactone may help reduce hair growth and testosterone levels in some women with hirsutism.
4 citations
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February 1983 in “Journal of periodontology” A liquid protein diet significantly affected young rats' body weight but had little effect on their gingival collagen metabolism.
1 citations
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April 2015 in “The FASEB journal” UVB exposure increases skin proteins for retinoic acid synthesis and shifts their location, possibly affecting skin repair.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
10 citations
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February 2017 in “Hormone Molecular Biology and Clinical Investigation” Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.
35 citations
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July 2008 in “International Journal of Gynecology & Obstetrics” MPA improved hormonal imbalances and acne in women with PCOS without affecting metabolism.
4 citations
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June 2022 in “Journal of food bioactives” Eating plant-based anti-inflammatories and antioxidants may help manage long-term COVID-19 health issues.
52 citations
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June 2014 in “PLANT PHYSIOLOGY” Arabidopsis plants adjust gene expression to maintain balance when auxin pathways are disrupted.