research The Ichthyoses: A Guide to Clinical Diagnosis, Genetic Counseling and Therapy
Effective management of ichthyoses requires genetic counseling and appropriate treatments.
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research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research Androgen action on human skin – from basic research to clinical significance
Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands
The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
research Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells
Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals
The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
research Considerations on Hair Research and Hair Growth
The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.
research Homology Modeling of 5-alpha-Reductase 2 Using Available Experimental Data
Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
research Unwanted hair.
Women with excessive hair growth often have hormonal issues and need medical advice and treatment.
research Systematic investigation of a potential epidemiological and genetic association between male androgenetic alopecia and COVID‐19
No significant link between male pattern baldness and COVID-19 severity was found.
research Low-Level Laser Therapy (LLLT) in Wound Healing
Low-Level Laser Therapy helps heal wounds and regenerate tissue when used correctly.
research [Hypothyroidism and hyperprolactinemia as a possible cause of androgenetic alopecia in the female].
Hypothyroidism and hyperprolactinemia may cause hair loss in women.
research Michaelis-Menten Kinetic Modification: The Space Pharmaceuticals Bioavailability Approaches Finasteride
Microgravity may increase drug bioavailability, potentially reaching up to 80%.
research Association Between Stress and Bilateral Symmetrical Alopecia in Free-Ranging Formosan Macaques (Macaca Cyclopis) in A High-Population-Density Area
Stress likely causes hair loss in Formosan macaques.
research 666 Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in follicular dystrophy and primary cicatricial alopecia
Mutations in Far2 mice cause hair loss due to sebaceous gland issues.
research The Effect of Drugs on Hair
Drugs can change hair growth and this is important because it can upset people.
research Dermatologic Clinics: Hair Disorders
Understanding androgen metabolism and thorough medical history are crucial for assessing and treating hair disorders.
research Anticonvulsant hypocalcaemia.
Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.
research 072 Covid-19 and male androgenetic alopecia: Systematic investigation of a potential epidemiological and genetic association
No significant link between male pattern baldness and severe Covid-19, but some shared biological pathways exist.
research An Unusual Form of Vitamin D-Dependent Rickets in a Child: Alopecia and Marked End-Organ Hyposensitivity to Biologically Active Vitamin D
The child's body didn't respond well to vitamin D, causing hair loss and rickets.
research Serum Androgens and Genetic Linkage Analysis in Early Onset Androgenetic Alopecia
Early onset hair loss linked to genetics and androgen levels.
research Idiopathic hirsutism: Is it really idiopathic or is it misnomer?
Idiopathic hirsutism might not be truly idiopathic but could be an early stage of hyperandrogenic disorders.
research The coudability sign of alopecia areata: the real story
The document concludes that anticonvulsants like phenytoin may cause skin reactions by affecting tryptophan metabolism and suggests researching vitamin levels in patients with drug reactions.
research Lichen planus pigmentosus and lichen planopilaris
Some people with lichen planus pigmentosus might later develop frontal fibrosing alopecia.
research Nonscarring alopecias
Male pattern hair loss affects up to 80% of men due to genetics and hormone sensitivity.
research Age-related downregulation of dihydrotestosterone-inactivating enzymes in human scalp sebaceous glands
Age-related changes in scalp glands may affect hair health, but sulforaphane might help.
research Age-related downregulation of dihydrotestosterone-inactivating enzymes in human scalp sebaceous glands
As people age, certain enzymes in scalp glands decrease, affecting hair health.
research Resident macrophages of the lung and liver: The guardians of our tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
research Zinc, Copper, and Iron in Selected Skin Diseases
Zinc, copper, and iron are important for skin health and may help diagnose skin diseases.