January 2026 in “Metabolites” This study investigates the molecular connections between obesity and immune vulnerability by analyzing gene expression profiles across various tissues, including liver, skeletal muscle, blood, and adipose tissues. The research identifies differentially expressed genes (DEGs) and highlights the significant roles of RPL15 and RBM39 genes. It finds that cancer, particularly leukemia, lymphoma, and gastric cancer, is strongly associated with obesity. The study also reveals a host-pathogen interaction network with Influenza A virus showing the highest interaction. Key metabolites common across tissues include 2-Oxoglutarate, Adenosine, Succinate, and D-mannose. The findings suggest a link between obesity and immune-related processes, with potential overlaps in pathways related to viral infections, cytokine signaling, and insulin metabolism, indicating a possible interaction between immune and metabolic processes in obese individuals. Further experimental validation is needed to confirm these relationships.
July 2025 in “Journal of Investigative Dermatology” Three molecular subtypes of advanced skin T-cell lymphoma were identified, with potential biomarkers for predicting treatment response and disease progression.
9 citations
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February 2022 in “BMC Genomics” Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.
11 citations
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April 2017 in “Journal of The European Academy of Dermatology and Venereology” Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
218 citations
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September 2012 in “Gastroenterology” Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
3 citations
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July 2024 in “Skin Research and Technology” 13 citations
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July 2024 in “BMC Genomics” New genes and markers can help breed better cashmere goats.
January 2025 in “EXPERIMENTAL ANIMALS” Gamma-ray exposure improves genome editing efficiency in mice using the i-GONAD method.
14 citations
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May 2020 in “Drug Testing and Analysis” A new method was created to measure metformin in hair, showing potential for monitoring treatment and medical investigations.
April 2023 in “Medizinische Genetik” New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.
432 citations
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April 2014 in “Nature communications” A mother's diet at conception can cause lasting genetic changes in her child.
13 citations
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March 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
1 citations
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February 2023 in “Frontiers in Endocrinology” Childhood growth hormone deficiency can be accurately diagnosed using gene expression data and random forest analysis.
5 citations
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November 2022 in “Animal Genetics” Genomic research can help improve the quality and production of natural fibers in animals.
10 citations
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May 2016 in “bioRxiv (Cold Spring Harbor Laboratory)” Lipid metabolism affects wool thickness in sheep.
August 2025 in “BMC Genomics” Certain genes contribute to stronger hooves in barefoot racing horses.
August 2018 in “Zenodo (CERN European Organization for Nuclear Research)” New techniques can record electromagnetic fields in hair follicles for potential medical use.
September 2021 in “European Neuropsychopharmacology” The research explores how gut bacteria and sleep patterns are related in mental health disorders.
Defective protein folding due to a mutation is key in ANE syndrome.
January 2024 in “Metabolites” Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.
7 citations
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August 2017 in “PloS one” Key genes linked to hair growth and cancer were identified in hairless mice.
12 citations
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January 2000 in “Biochemical and Biophysical Research Communications” The study mapped keratin 15 and 19 genes, aiding future genetic disorder research.
January 2022 in “Figshare” Melatonin affects when and how certain genes work during the growth of goat hair follicles.
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
November 2025 in “Communications Biology” Human hair contains many different molecules that change along its length, influenced by personal care products.
The atlas maps maize peptides, showing complex regulation and varied roles across tissues and stages.
May 2026 in “The FASEB Journal” This study investigates the role of microRNAs (miRNAs) in androgenetic alopecia (AGA) by integrating miRNA data with existing mRNA sequencing profiles to construct miRNA-mRNA regulatory networks. The research highlights the downregulation of predicted target genes related to structure modulation, suggesting that microenvironment remodeling may contribute to hair follicle stem cell dysfunction in AGA. An AGA model using organ-cultured balding hair follicles was established to explore miRNA roles, revealing that miR-146b-5p could promote hair growth and improve the inflammatory microenvironment in AGA hair follicles. This miRNA presents a promising target for AGA treatment.
April 2024 in “Human genomics” Identified genes linked to male-pattern baldness may help develop new treatments.