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Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Scalp cooling significantly reduces hair loss in chemotherapy patients.

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

MRI helps distinguish between pituitary adenomas and craniopharyngiomas, guides treatment for pediatric CNS tumors, and assesses rhinocerebral mucormycosis with a high mortality rate in transplanted patients.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Icariin can regulate macrophages and may help treat inflammation, cancer, bone disorders, and fibrotic diseases.

HPV16-transformed cells can change human skin cell properties, aiding tumor growth.

Aging men face unique health issues like erectile dysfunction, prostate problems, and baldness.

Wedelolactone may help treat inflammation, infections, cancer, bone loss, and organ damage.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

PRMT5 inhibitors effectively fight adenoid cystic carcinoma in salivary glands.

Nano-Pulse Stimulation™ Therapy is more effective and less damaging than cryoablation for treating melanoma tumors in mice.

Low-dose DMSO may help treat castration-resistant prostate cancer by reducing key cancer cell receptors.

The guidelines aim to find treatable prostate cancer early while avoiding unnecessary tests and treatments.