research Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives.
New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
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570-600 / 1000+ results research A method for simultaneous analysis of androgens, dutasteride and finasteride in human serum by liquid chromatography tandem mass spectrometry
A new method was developed to analyze certain hormones and drugs in human blood efficiently.
research A new catalyst for organic synthesis: mercuric triflate
Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
research Picogram determination of finasteride in human plasma and semen by high-performance liquid chromatography with atmospheric-pressure chemical-ionization tandem mass spectrometry
Method detects finasteride in plasma and semen with high sensitivity and accuracy.
research Spermidine/spermine-N1-acetyltransferase: a key metabolic regulator
SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
research FDA declines approval of testosterone drug for third time
The FDA rejected a testosterone drug again due to safety concerns.
research 10. EVALUATION OF THE EFFICACY AND SAFETY FOR THE COMBINATION USE OF ORAL AND TOPICAL TRANEXAMIC ACID IN THE TREATMENT OF MELASMA AT HO CHI MINH CITY DERMATOLOGY HOSPITAL
Oral and topical tranexamic acid effectively and safely improve melasma.
research Love is in the hair: arginine methylation of human hair proteins as novel cardiovascular biomarkers
Human hair protein modifications could potentially indicate heart disease risk.
research Synthesis of 4-amidinoimidazoles incorporating a cyanamide moiety : novel precursors for biologically important purines
research More about X‐linked testicular feminization of the mouse as a noninducible (is) mutation of a regulatory locus: 5α‐androstan‐3α‐17ß‐diol as the true inducer of kidney alcohol dehydrogenase and ß‐glucuronidase
A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
research (282) CONSEQUENCES OF ANABOLIC-ANDROGENIC STEROID ABUSE IN MALES: RESULTS FROM A META-ANALYSIS STUDY
Anabolic-androgenic steroids harm male hormone levels, sperm, metabolism, and can cause acne, hair loss, and breast growth.
research Arachis hypogaea L. Root Extract Mitigates Testosterone Propionate‐Induced Benign Prostatic Hyperplasia in ICR Mice by Suppressing Inflammation, Androgen Receptors, and Dihydrotestosterone
Arachis hypogaea L. root extract reduces prostate enlargement and inflammation in mice.
research N-(3,5-Dimethylphenyl)-3-Methoxybenzamide (A3B5) Targets TRP-2 and Inhibits Melanogenesis and Melanoma Growth
A3B5 can reduce skin pigmentation and slow melanoma growth.
research Dissolving microneedles incorporating kopexil multicomponent crystals for improved transdermal delivery
Multicomponent crystals in microneedles improve drug delivery for hair loss treatment.
research The Opiate Antagonist, Naltrexone, in the Treatment of Trichotillomania
Naltrexone did not significantly reduce hair pulling but improved cognitive flexibility.
research New approach to 3-oxo-4-aza-5α-androst-1-ene-17β-(--butylcarboxamide)
A new method was developed to make finasteride for treating hair loss.
research Maternal Melatonin Contributes to Offspring Hair Follicle Development Through Transcriptional Regulation of the AP-1 Complex and MAPK Pathway
Maternal melatonin improves offspring hair growth by affecting specific proteins and pathways.
research Bachmann–Bupp syndrome and treatment
DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.
research Repetitive Transcranial Magnetic Stimulation for Treatment of Trichotillomania: Case Series
rTMS may help treat trichotillomania in some patients.
research Improved synthesis of finasteride
The new method makes finasteride production cheaper and safer for industry.
research Topical spermine and putrescine stimulated DNA synthesis in the hairless mouse epidermis
Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.
research The first clinical experience on efficacy of topical flutamide on melasma compared with topical hydroquinone: a randomized clinical trial
Topical flutamide works as well as hydroquinone for melasma but needs more safety checks.
research Medicolegal aspects of doping in football
Doping in football faces legal challenges with testosterone limits, hair loss treatments, and recreational drug use.
research 황백(黃柏)이 전립선비대증(前立腺肥大症) Rat에 미치는 영향
Phellodendri Cortex Extract may help treat enlarged prostate.
research HERBAL CREAMS OF REISHI EXTRACT AND TEA TREE OIL FOR HIRSUTISM–AN IN VIVO STUDY
Tea tree oil cream effectively reduces hair growth.
research Human Hair in Personal Identification and Documenting Drug and Substance Abuse
Human hair is valuable for identifying people and detecting drug use.
research Epitestosterone—an endogenous antiandrogen?
Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.
research The effects of topical diazoxide on hair follicular growth and physiology of the stumptailed macaque
Diazoxide applied to the skin can increase hair growth without harmful side effects.
research Highly efficient nucleophilic addition of alkyl Grignard reagents to 17-ketosteroids in the presence of cerium(III) chloride: Synthesis of 17α-propyl-17β-hydroxy-4-androsten-3-one, an androgen receptor antagonist
Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.
research Thallium in rodenticide- banned or not..!!!- Two case reports
Thallium poisoning is dangerous but treatable with specific medical interventions.