research Advances in the mechanism and new therapies of alopecia areata
New treatments targeting the JAK signaling pathway, especially JAK inhibitors, show promise for alopecia areata.
Search
for
Sort by
Research
960-990 / 1000+ results research Is there a ‘gut–brain–skin axis’?
Probiotics may help reduce stress-related skin issues and improve hair growth.
research Resident human dermal γδT-cells operate as stress-sentinels: Lessons from the hair follicle
Human dermal γδT-cells respond to stress in hair follicles, contributing to hair loss.
research Research Relevant Conditions and Pathology in Nonhuman Primates
Nonhuman primates are valuable in research but their natural health variations can complicate study results.
research Could Vaccination against COVID-19 Trigger Immune-Mediated Inflammatory Diseases?
COVID-19 mRNA vaccines may increase the risk of flare-ups in certain inflammatory diseases.
research Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force “Dermatology for Cancer Patients” International Study
Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.
research Does Complement Have a Role in the Pathogenesis of Alopecia Areata?
The complement system might be involved in the development of alopecia areata and could lead to new treatments.
research Understanding the Association Between Mental Health and Hair Loss
Mental health and hair loss are linked, and treating both can improve well-being.
research Insights into Alopecia Areata: A Systematic Review of Prevalence, Pathogenesis, and Psychological Consequences
Alopecia Areata affects people of all ages worldwide, is likely caused by genetic and environmental factors, and can lead to stress and depression, highlighting the need for treatments that address both physical and mental health.
research Topical metformin as a novel therapy for alopecia areata due to its immunologic effects
Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
research Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients
Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.
research The correlation between corona virus disease 2019 and alopecia areata: a literature review
COVID-19 can increase the risk of hair loss, especially in people over 40.
research Pediatric alopecia areata following COVID‐19 infection
Some children may develop hair loss after having COVID-19.
research A recently characterized, underdiagnosed cause of female androgenetic alopecia and polycystic ovarian syndrome: non-classical 21 hydroxylase deficiency
Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.
research 0085 Th1/Th2 balance, IFN-γ–MHC-I axis, and regulatory T cells define therapeutic response endotypes in alopecia areata
research Epidermal growth factor receptor/mitogen-activated kinase inhibitor treatment induces a distinct inflammatory hair follicle response that includes collapse of immune privilege
EGFRi/MEKi treatments cause hair follicles to lose some immune protection, leading to inflammation.
research Alopecia Areata is associated with MICA and an extended HLA haplotype
Certain genes are linked to the risk of developing Alopecia Areata.
research 51223 A novel human disease model of alopecia areata to evaluate benefit of the DHODH inhibitor farudodstat
Farudodstat may effectively treat alopecia areata without harmful side effects.
research 90 Exploring the therapeutic potential of DHODH inhibitor farudodstat for alopecia areata treatment in a novel ex vivo model of human hair follicle immune privilege collapse
Farudodstat may effectively treat alopecia areata without harming hair follicles.
research LB1777 A novel ex vivo model of human hair follicle immune privilege collapse reveals the potential of farudodstat, a DHODH inhibitor, as a therapeutic for alopecia areata treatment
Farudodstat may help treat alopecia areata by protecting hair follicles.
research Acquired and inheritedhair disorders
Hair disorders can be genetic or acquired, affecting hair growth and loss differently.
research ISIDLB1777 - A novel ex vivo model of human hair follicle immune privilege collapse reveals the potential of farudodstat, a DHODH inhibitor, as a therapeutic for alopecia areata treatment
Farudodstat may effectively treat alopecia areata by protecting hair follicles without harmful effects.
research 061 Selective inhibition of tyrosine kinase 2 prevents and restores interleukin-12-induced hair follicle immune privilege collapse: a novel approach to alopecia areata therapy?
Blocking IL-12 can help treat alopecia areata by preventing hair follicle immune issues.
research Bioinformatics analysis of EST segment from goat
Goat skin has more keratin genes, while the mammary gland has more immunity-related genes.
research 700 Tyrosine kinase 2 inhibition rescues hair follicles from IL-12–mediated immune privilege collapse and reverses the induction of human alopecia areata in a humanized mouse model
Inhibiting TYK2 can restore hair growth in alopecia areata.
research An in silico approach to the identification of potential proteomic and genomic diagnostic biomarkers for primary cicatricial alopecia
Certain genes and proteins may help diagnose and treat primary cicatricial alopecia.
research Transforming 300 billion points of data into diagnostics, therapeutics and new insights into disease
Large data can lead to new medical discoveries and personalized medicine.
research Pengaruh self affirmation therapy terhadap tingkat ansietas mahasiswa Stikes Panti Waluya Malang sebelum melakukan presentasi tugas terstruktur
Self-affirmation therapy significantly reduces student anxiety before presentations.
research Distribution of major histocompatibility antigens in normal skin
Major histocompatibility antigens are found in specific skin cells and structures, but not in sweat glands.
research Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2.
A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.