165 citations
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September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
162 citations
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The new "differential stripping" method effectively measures how much substance gets into hair follicles.
157 citations
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May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
153 citations
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August 2002 in “Dermatologic Surgery” Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.
147 citations
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September 2006 in “Developmental Cell” Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
138 citations
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August 1985 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth in male pattern baldness.
137 citations
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May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
121 citations
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March 1989 in “Journal of Investigative Dermatology” Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.
115 citations
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September 2000 in “The Lancet” Early hair loss may indicate risk of insulin resistance.
109 citations
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July 1984 in “Circulation” Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.
94 citations
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June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
90 citations
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January 2003 in “The Journal of Urology” Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.
88 citations
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February 2008 in “Journal of Medicinal Chemistry” Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
87 citations
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April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
85 citations
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May 2019 in “Journal of neuroendocrinology” The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
82 citations
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August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
80 citations
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August 2002 in “Journal of Dermatology” Best hair growth results from combining finasteride and minoxidil.
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February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
77 citations
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January 1989 in “Clinical Infectious Diseases” Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.
75 citations
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March 2009 in “Journal of The American Academy of Dermatology” CCCA is a hair loss type affecting African women, possibly caused by grooming and chemicals, with various treatments and needing more research.
72 citations
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December 1983 in “Journal of Investigative Dermatology” Minoxidil helps hair cells live longer and grow longer.
71 citations
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September 2007 in “Cancer” Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.
70 citations
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April 1990 in “Journal of The American Academy of Dermatology” Minoxidil treatment increased hair growth for up to 5 years, requiring twice daily application.
63 citations
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January 1992 in “Experimental Neurology” Chickens exposed to loud noise can quickly regain hearing mostly due to repair of the tectorial membrane, not just hair cell regeneration.
60 citations
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November 2013 in “Development” Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
60 citations
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October 2009 in “Dermatology” Alopecia areata may appear differently depending on the individual's type of hair loss and scalp condition.
60 citations
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June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
60 citations
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February 1997 in “Journal of Dermatological Science” Liposomes can safely and effectively deliver substances to mouse hair follicles, potentially useful for human hair treatments.
60 citations
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January 1989 in “Toxicologic Pathology” Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.
58 citations
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July 1986 in “Journal of The American Academy of Dermatology” Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.