28 citations
,
March 2013 in “Journal of Investigative Dermatology” Kv1.3 blockers may help treat alopecia areata and promote hair regrowth.
26 citations
,
December 2020 in “Nature metabolism” Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
23 citations
,
January 2021 in “Scientific Reports” Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
23 citations
,
June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
23 citations
,
June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
21 citations
,
December 1994 in “British Journal of Dermatology” Sheep dermal papillae can help form hair follicles in skin models.
14 citations
,
April 2016 in “PloS one” The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
6 citations
,
April 2017 in “Journal of Dermatological Science” Ovariectomized mice mimic postmenopausal hair loss, and estradiol helps maintain hair density.
5 citations
,
March 2019 in “Scientific Reports” The technique can isolate cells to help treat skin pigmentation issues.
5 citations
,
January 2019 in “Methods in molecular biology” Multiphoton microscopy can effectively image live cells in cornea, skin, and hair follicles over time.
5 citations
,
April 2018 in “Journal of Dermatological Science” Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.
5 citations
,
August 2011 in “Journal of Dermatological Science” Dentin sialoprotein and phosphophoryn are present in rodent hair follicles and may help hair growth and development.
4 citations
,
March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
3 citations
,
November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
3 citations
,
January 2023 in “Materials horizons” The new biomaterial helps grow blood vessels and hair for skin repair.
2 citations
,
March 2020 in “Developmental cell” Stress can cause hair to turn gray by depleting pigment-producing cells through the release of a stress hormone.
1 citations
,
September 2008 The herbal extract promoted faster hair regrowth in mice.
RNase L hinders hair follicle regeneration by altering immune signals.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
April 2019 in “Journal of Investigative Dermatology” Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.
Shh and Dhh affect skin development and can cause tumors, while Ihh does not.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing certain immune cells in mice causes their hair to enter the growth phase earlier than usual.
October 2021 in “Journal of Investigative Dermatology” Dkk4 protein is necessary for the proper development and arrangement of hair follicles.
April 2018 in “Journal of Investigative Dermatology” Lymphocytes, a type of immune cell, are crucial for wound healing as they help remodel damaged areas and reduce inflammation.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.
September 2016 in “Journal of dermatological science” Human induced pluripotent stem cells can be used to create cells that help grow hair.
December 2013 in “Appetite” A defective gene causes hair loss and taste insensitivity in BTBR mice.
December 2012 in “Journal of dermatological science” Hair follicles help attract immune cells to minor skin injuries.
May 2012 in “The Journal of Nuclear Medicine” Hair stem cells were tracked in mice using a special imaging technique, showing that it's possible to monitor hair growth this way.