1 citations
,
December 2023 in “JAAD International” Mast cells may significantly contribute to central centrifugal cicatricial alopecia.
23 citations
,
April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
3 citations
,
April 2018 in “Journal of Investigative Dermatology” CCCA may be a fibroproliferative disorder, and anti-fibrotic therapies could help.
December 2018 in “International journal of women’s dermatology” Early diagnosis and strong corticosteroids are crucial for managing lymphocytic cicatricial alopecia.
11 citations
,
January 2022 in “Experimental Dermatology” Severe CCCA may be biologically and clinically different from milder forms.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Potential therapeutic targets for scarring hair loss are identified.
September 2022 in “Skin appendage disorders” Seborrheic dermatitis may contribute to the development of central centrifugal cicatricial alopecia.
September 2025 in “Cureus” There is no standard treatment for CCCA, and practices vary widely.
1 citations
,
October 2022 in “Hair Transplantation” Surgical correction of cicatricial alopecia requires careful planning, with excision preferred over hair transplantation, and surgery should be delayed for stable conditions.
July 2023 in “Nasza Dermatologia Online” More research is needed on CCCA in children, especially Black and Asian adolescents.
17 citations
,
August 2004 in “International Journal of Dermatology” Prolonged pressure on the scalp can cause permanent hair loss.
25 citations
,
September 2010 in “Journal of Cutaneous Medicine and Surgery” The study found that Central Centrifugal Cicatricial Alopecia mainly affects middle-aged African descent women, is linked to certain hair care practices and genetics, and often goes undiagnosed for years.
December 2024 in “Texila international journal of public health” Trichoscopy effectively diagnoses and monitors cicatricial alopecias, reducing the need for biopsies.
March 2022 in “JAAD case reports” Accurate diagnosis is crucial for effective treatment of hair loss.
Alopecia areata is an autoimmune disease that targets hair follicles.
October 2021 in “Experimental Dermatology” Certain genes and proteins may help diagnose and treat primary cicatricial alopecia.
August 2023 in “JAAD international” Most patients with Central Centrifugal Cicatricial Alopecia at the reviewed institution were middle-aged Black women, often with no symptoms, and commonly treated with topical medications.
32 citations
,
March 2008 in “SKINmed Dermatology for the Clinician” Accurate diagnosis and tailored treatment are crucial for managing complex hair loss conditions.
5 citations
,
October 2019 in “JAAD Case Reports” These hair loss conditions might be part of a spectrum, not separate issues.
13 citations
,
March 2016 in “Journal of Cutaneous Pathology” Some people's hair loss is caused by multiple factors, with the most common being a mix of AGA and CCCA.
May 2023 in “Archives of dermatological research” Some factors like thyroid disease, diabetes treatment, hair dryers, natural hairstyles, and scalp conditions can affect the treatment results for a hair loss condition called CCCA.
July 2025 in “JAAD Case Reports” A thorough assessment and combined treatment are crucial for managing complex alopecia, especially in patients with skin of color.
1 citations
,
May 2024 in “Skin Appendage Disorders” Early diagnosis with trichoscopy can improve management and quality of life for CCCA patients.
21 citations
,
February 2009 in “Journal of the American Academy of Dermatology” Some cases of tinea capitis, a fungal scalp infection, can look like scarring hair loss due to the body's immune response and the fungus itself.
6 citations
,
December 2018 in “The American Journal of Dermatopathology” Early shedding of the inner root sheath in noninflamed hair follicles is a relatively specific sign of Central Centrifugal Cicatricial Alopecia.
42 citations
,
January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
15 citations
,
November 1998 in “Australasian Journal of Dermatology” Cicatricial pemphigoid rarely affects the scalp but is hard to treat when it does.
July 2018 in “Elsevier eBooks” Early treatment is key to prevent permanent hair loss from scalp conditions that cause scarring.
October 2015 in “CRC Press eBooks” Classifying alopecia helps diagnose and treat different types of hair loss accurately.
16 citations
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January 2011 in “Indian Journal of Dermatology” Most patients with cicatricial alopecias face significant psychological and social challenges due to their hair loss.