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GlossaryMicroarray Analysis

examines gene expression levels across thousands of genes simultaneously

Microarray Analysis, also known as Gene Chip Analysis or DNA Microarray Analysis, is a laboratory technique used to study the expression levels of many genes simultaneously. It involves placing thousands of DNA sequences on a small chip, then exposing it to a sample to see which genes are active or inactive. This method is particularly useful for understanding complex genetic conditions, such as alopecia, by identifying which genes are involved in the disease process.

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research Microarray analysis of androgenetic and senescent alopecia: Comparison of gene expression shows two distinct profiles

27 citations , July 2013 in “Journal of Dermatological Science”

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors by Microarray Analysis

research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors (SKP) by Microarray Analysis

6 citations , April 2010 in “Cellular Reprogramming”

Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.

research Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis

6 citations , January 2010 in “Springer eBooks”

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.

Microarray Analysis Reveals Distinct RNA Expression Profiles in Endothelial Progenitor Cells Exposed to Pro-Inflammatory Environment or Oxidized LDL

research Microarray analysis reveals distinct RNA expression profiles in endothelial progenitor cells exposed to pro-inflammatory environment or oxidized LDL

December 2015 in “Vascular Pharmacology”

Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.

research DNA Microarray and Bioinformatic Analysis Reveals the Potential of Whale Oil in Enhancing Hair Growth in a C57BL/6 Mice Dorsal Skin Model

May 2024 in “Genes”

Whale oil significantly promotes hair growth and may be a safe, effective alternative to minoxidil.

research DNA Microarray and Bioinformatic Analysis Reveals the Potential of Whale Oil in Enhancing Hair Growth in a C57BL/6 Mice Model

April 2024

Whale oil may safely and effectively promote hair growth.

Diagnostic Value of Chromosomal Microarray Analysis in Patients With Congenital Anomalies and Dysmorphic Features; Details of Two New Patients With 2q33 Deletions

research DIAGNOSTIC VALUE OF CHROMOSOMAL MICROARRAY ANALYSIS IN PATIENTS WITH CONGENITAL ANOMALIES AND DYSMORPHIC FEATURES; DETAILS OF TWO NEW PATIENTS WITH 2q33 DELETIONS

December 2024 in “Kırıkkale Üniversitesi Tıp Fakültesi Dergisi”

Chromosomal microarray analysis is important for diagnosing rare genetic variations and guiding treatment.

research Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus

February 2024 in “Veterinary sciences”

Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.

research A Microarray-Based Analysis Reveals that a Short Photoperiod Promotes Hair Growth in the Arbas Cashmere Goat

40 citations , January 2016 in “PLoS ONE”

Shorter daylight increases hair growth in Cashmere goats.

Infundibular Protein and RNA Microarray Analyses from Affected and Clinically Non-Affected Scalp in Male Androgenetic Alopecia Patients

research Infundibular protein and RNA microarray analyses from affected and clinically non-affected scalp in male androgenetic alopecia patients

8 citations , March 2017 in “Experimental Dermatology”

Finasteride helps female-pattern hair loss.

research Transcriptome Analysis Methods: From the Serial Analysis of Gene Expression and Microarray to Sequencing new Generation Methods

2 citations , December 2023 in “Biointerface Research in Applied Chemistry”

RNA-Seq is now the standard for detailed gene expression analysis.

research Gene profile analysis of colorectal cancer cell lines by cDNA macroarray

10 citations , May 2007 in “Oncology Reports”

Colorectal cancer's ability to spread is due to changes in many genes, not just one.

Analysis of Thymosin β4 and Vascular Endothelial Growth Factor Expression in Normal Human Tissues Using Tissue Microarray

research Analysis of Thymosin β4 and Vascular Endothelial Cell Growth Factor (VEGF) Expression in Normal Human Tissues Using Tissue Microarray

December 2009 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji”

Thymosin β4 and VEGF are important for blood vessel formation in many organs.

research Food Deprivation-induced Expression of Minoxidil Sulfotransferase in the Hypothalamus Uncovered by Microarray Analysis

36 citations , March 2002 in “Journal of Biological Chemistry”

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.

research Effect of Sun exposure-induced ferroptosis mechanisms on pathology and potential biological processes of primary melanoma by microarray data analysis

12 citations , September 2022 in “Frontiers in Genetics”

Enhancing CD8+ T cell function to induce ferroptosis in tumor cells may help treat skin melanoma.

research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis

47 citations , July 2004 in “Journal of Dermatological Science”

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Similar Response Patterns to Topical Minoxidil Foam 5% in Frontal and Vertex Scalp of Men with Androgenetic Alopecia: A Microarray Analysis

research Similar response patterns to topical minoxidil foam 5% in frontal and vertex scalp of men with androgenetic alopecia: a microarray analysis

19 citations , September 2014 in “British Journal of Dermatology”

Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.

Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus Terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis

research Elucidation of the Potential Hair Growth-Promoting Effect of Botryococcus terribilis, Its Novel Compound Methylated-Meijicoccene, and C32 Botryococcene on Cultured Hair Follicle Dermal Papilla Cells Using DNA Microarray Gene Expression Analysis

5 citations , May 2022 in “Biomedicines”

Botryococcus terribilis and its compounds may promote hair growth and improve hair health.

research Discovery of genes and proteins possibly regulating mean wool fibre diameter using cDNA microarray and proteomic approaches

6 citations , May 2020 in “Scientific reports”

Researchers identified genes and proteins that may influence wool thickness in sheep.

Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle?

research Mind the (Gender) Gap: Does Prolactin Exert Gender and/or Site-Specific Effects on the Human Hair Follicle?

36 citations , November 2009 in “Journal of Investigative Dermatology”

Prolactin may affect hair growth differently based on gender and scalp area.

research Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel

4 citations , May 2020 in “PLOS ONE”

Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.

research Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein

November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

research Diagnostic Modalities in Trichology - An Update

January 2015 in “Hair therapy & transplantation”

New hair and scalp disease diagnosis methods are important for correct treatment.

research In This Issue

December 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Scientists found a new method using 3D cell cultures to grow human hair which may improve hair restoration treatments.

research The genetics of alopecia areata

16 citations , December 2001 in “Dermatologic Therapy”

Alopecia areata has a complex genetic basis that was not fully understood as of 2001.