140 citations
,
December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
131 citations
,
May 2015 in “Experimental Dermatology” Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.
86 citations
,
August 2021 in “Polymers” Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
4 citations
,
March 2013 in “The American Journal of Cosmetic Surgery” Melanin absorbing light is necessary but not enough for effective hair removal by light treatment.
July 2025 in “Journal of Drug Delivery Science and Technology” Hydrogel microneedles with special nanoparticles and growth factor improve hair growth better than minoxidil for hair loss treatment.
2 citations
,
January 2023 in “Dermatologic Therapy” CEFFE injections effectively and safely improve postinflammatory hyperpigmentation.
January 2018 in “Sohag Medical Journal” August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Machine learning optimized microneedles promote hair regrowth better than minoxidil without safety risks.
19 citations
,
July 2019 in “Biomedical Microdevices” Microneedles can cause side effects like infection and allergic reactions, and precautions like test spots and sunscreen are recommended.
17 citations
,
May 2023 in “Pharmaceutics” Microneedles can precisely deliver cancer treatments with fewer side effects.
January 2022 in “Indian dermatology online journal” Pigmented papules on the ear can be a rare skin condition called cutaneous amyloidosis, treatable with topical tretinoin.
December 2021 in “The Korean Society of Beauty and Art” A microneedle patch system was developed for quick, convenient, and efficient delivery of hair loss treatment drug, Finasteride.
53 citations
,
January 2014 in “Journal of Cutaneous and Aesthetic Surgery” Microneedling combined with triamcinolone can safely stimulate faster hair regrowth in people with Alopecia Areata.
22 citations
,
August 2013 in “PLOS ONE” The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
2 citations
,
May 2018 in “Dermatologic Surgery” 1 citations
,
December 2024 in “Pomeranian Journal of Life Sciences” Microneedling helps heal and rejuvenate skin and gums effectively.
Hair follicles can effectively absorb nano-sized particles, making them potential targets for localized drug delivery.
November 1995 in “Dermatologic Surgery” The concentric mini-micrografting method is effective for extensive baldness, creating a natural look and efficiently using donor hair.
28 citations
,
November 2020 in “Journal of Controlled Release” A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
Microneedling may help treat some autoimmune skin conditions, but more research is needed.
February 2026 in “International Journal of Pharmaceutics”
1 citations
,
March 2024 in “Ophthalmic Plastic and Reconstructive Surgery” A pilomatrixoma in the eyebrow can cause hair loss and skin lightening.
92 citations
,
June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.
1 citations
,
May 2015 in “Dermatologic Therapy” The microstrip technique for hair transplantation is effective and discreet for patients needing fewer than 1500 grafts.
2 citations
,
May 2002 in “PubMed” Micro-graft hair transplantation is an effective, simple, and painless method for permanent hair restoration in men and women.
13 citations
,
February 2020 in “Journal of the American Academy of Dermatology” Microneedling and oral tranexamic acid both improve facial melasma, but microneedling shows more sustained benefits.
January 2026 in “JPRAS Open” PDLLA scalp injections improved hair regrowth in most patients with non-scarring alopecia.
17 citations
,
April 2002 in “Contact Dermatitis” Minoxidil 5% caused skin discoloration in a man using it for hair loss.
Bubble microneedles effectively deliver drugs through the skin and mouth, improving treatment speed and efficiency.
May 2026 in “Journal of Nanobiotechnology” A new peptide delivered through microneedles can effectively promote hair regrowth.