research Sacituzumab tirumotecan (sac-TMT/MK-2870/SKB264): a novel antibody–drug conjugate in breast cancer
Sacituzumab tirumotecan shows promise in treating breast cancer with manageable side effects.
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270-300 / 1000+ results research Neoadjuvant Therapy with Disitamab Vedotin in Treating Muscle-Invasive Bladder Cancer: A Case Report
Gemcitabine and Disitamab Vedotin effectively and safely reduced bladder cancer in a patient.
research Cyclosporine Therapy for Bullous Erythema Multiforme
Cyclosporine cleared a woman's resistant skin condition quickly and kept it away for over a year.
research Biological therapy in the treatment of melanoma
Biological therapy boosts the immune system to effectively fight melanoma.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/assets/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research [Contribution to one world, one health: a dog with demodicosis.].
Ivermectin, antibacterial drugs, and beta-glucan successfully treated a police dog's demodicosis.
research Comparison of Systemic Mycophenolate Mofetil with Topical Clobetasol in Lichen Planopilaris: A Parallel-Group, Assessor- and Analyst-Blinded, Randomized Controlled Trial
Topical clobetasol is recommended over mycophenolate mofetil for treating Lichen Planopilaris due to better safety and patient satisfaction.
research Correction to: Toxicity of the pharmaceuticals finasteride and melengestrol acetate to benthic invertebrates
Finasteride and melengestrol acetate are toxic to benthic invertebrates.
research MANAGEMENT OF SCABIOSIS WITH ANCYLOSTOMIOSIS IN LOCAL BREED PUPPY
The treatment was effective for the puppy's skin and intestinal infections.
research Identification of a Cyclosporine-Specific P450 Hydroxylase Gene through Targeted Cytochrome P450 Complement (CYPome) Disruption in Sebekia benihana
A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.
research Molecular and physiological mechanisms underlying the antifungal and nutrient acquisition activities of beneficial microbes
Certain beneficial microbes can fight fungi and help plants get nutrients.
research Increasing mupirocin resistance in pediatric methicillin-resistant Staphylococcus aureus skin and soft-tissue infections in New York: A genomic approach
There's a growing resistance to the antibiotic mupirocin in children's skin infections caused by MRSA in New York.
research Protective Role of Cepharanthine Against Equid Herpesvirus Type 8 Through AMPK and Nrf2/HO-1 Pathway Activation
Cepharanthine may help treat Equid herpesvirus type 8 by reducing oxidative stress.
research Hepatogenous Photosensitization Neonatal Calf Raised on Brachiaria decumbens Pasture
Early diagnosis and intervention can prevent liver-related skin issues in calves on certain pastures.
research Anaplasmosis concurrent with copper deficiency in a Salem Black kid
The young goat had anaplasmosis and copper deficiency.
research A phase 1b study of chemo-immunotherapy with pegylated liposomal doxorubicin and Pembrolizumab in estrogen receptor positive metastatic breast cancer
The treatment combination is safe and effective for some patients with this type of breast cancer.
research Medical Treatment of Liver Hydatidosis
Surgery is the main treatment for liver hydatidosis, but has risks; albendazole is the most effective drug but can have side effects.
research Fe-MOF@Quercetin Complex with Light-controlled Redox Modulation for Tumor Wound Repair
The study introduces a MIL-101-(Fe)@Quercetin (MQ) complex designed to address the challenge of balancing reactive oxygen species (ROS) levels for tumor recurrence inhibition and wound healing post-melanoma excision. The MQ complex, with its unique structure, allows for light-controlled redox regulation, generating ROS under laser irradiation to inhibit tumor growth while scavenging excess ROS to promote wound healing. In vivo experiments on a mouse melanoma wound model showed that MQ Microneedles (MQ@MNs) effectively manage ROS levels, demonstrating potential for improved melanoma wound treatment through controlled ROS modulation.
research Phase I-II trial of weekly bicalutamide in men with high PSA and negative biopsy
Weekly bicalutamide is safe and effective, with 50 mg/week recommended.
research Resolution of Waldenström's macroglubulinemia related isolated neutropenia by immunochemotherapy
Immunochemotherapy successfully treated neutropenia in a patient with Waldenström's macroglobulinemia.
research A MultifunctionalMOF Heterojunction for CombatingAntibiotic Resistance and Promoting Regenerative Immunity
A new treatment effectively kills antibiotic-resistant bacteria and helps wounds heal faster by boosting the immune response.
research Case Report: Analytically Confirmed Severe Albenzadole Overdose Presenting with Alopecia and Pancytopenia
Overdosing on veterinary albendazole can cause severe health issues like hair loss and low blood cell count.
research The use of photobiomodulation therapy in the treatment of hair cycle arrest in a Pembroke Welsh corgi
Light therapy successfully treated a dog's hair growth problem without side effects.
research Imported cutaneous Leishmaniasis in Japan
Albendazole can cause hair loss, and piroxicam can cause fixed drug eruption.
research Successful treatment of sebaceous adenitis in a rabbit with ciclosporin and triglycerides
A rabbit with sebaceous adenitis was effectively treated with ciclosporin and medium-chain triglycerides.
research The Effect of Butin on the Vitiligo Mouse Model Induced by Hydroquinone
Butin is effective in treating vitiligo in mice.
research Relation of Selenium, Vitamin E and Other Factors to Muscular Dystrophy in the Rabbit
Natural feedstuffs help reduce muscular dystrophy in rabbits more than selenium or vitamin E alone.
research Azathioprine hypersensitivity in bullous pemphigoid
A woman with bullous pemphigoid had an allergic reaction to azathioprine, but got better with alternative treatments.
research Formulation and clinical evaluation of niosomal methylene blue for successful treatment of acne
Niosomal methylene blue gel effectively improves moderate to severe acne.
research Repurposing Finasteride and Serotonin Reuptake Inhibitors as Novel Antimicrobials: A Dual-Action Approach to Target Bacterial and Fungal Pathogens
Duloxetine, escitalopram, and finasteride may be effective against bacteria and fungi.