4 citations
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November 2021 in “Journal of The American Academy of Dermatology” Bicalutamide may reduce unwanted hair growth caused by minoxidil in women with hair loss.
32 citations
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August 1996 in “Journal of Investigative Dermatology”
22 citations
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October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.
37 citations
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April 1979 in “The Journal of Clinical Pharmacology” Minoxidil effectively controls blood pressure but side effects may limit its use.
April 2022 in “Reactions Weekly” April 2023 in “Medicina Clínica (english Edition)”
1 citations
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January 2018 in “Side effects of drugs annual” Diuretics can cause serious side effects and should be used carefully.
9 citations
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June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
1 citations
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February 2020 in “Drug Design Development and Therapy” Low-dose Minoxidil combined with Spironolactone helps reduce hair loss and improve hair density in women, with some mild side effects.
33 citations
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May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
December 2025 in “International Journal of Dermatology” Combining low-dose oral minoxidil with immunomodulators shows promise for treating alopecia areata but needs more research.
8 citations
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June 2023 in “European Journal of Endocrinology” The inhibitor affects androgen metabolism but not ovarian function.
February 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Minoxidil 0.25 mg with spironolactone 25 mg reduces hair loss and improves hair density in women.
May 2023 in “Frontiers in Endocrinology” Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
28 citations
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January 2004 in “British Journal of Pharmacology” Minoxidil protects heart and improves recovery.
February 2026 in “Journal of the American Academy of Dermatology” The combination of spironolactone and low-dose minoxidil is generally safe for treating hair loss in adult females, with mostly mild side effects.
17 citations
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December 2015 in “Bioorganic & Medicinal Chemistry” 3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.
April 2016 in “Journal of The American Academy of Dermatology” Some blood pressure medications are linked to a higher risk of skin cancer.
17 citations
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April 1975 in “The Journal of Pediatrics” Minoxidil effectively controls severe high blood pressure in children with few side effects.
26 citations
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January 1978 in “Nephron” Minoxidil lowers blood pressure effectively but may cause side effects.
March 2024 in “Journal of the American Academy of Dermatology”
45 citations
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January 1981 in “Annals of Internal Medicine” Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
October 2025 in “CRC Press eBooks”
34 citations
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January 1977 in “American Journal of Cardiology”
6 citations
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January 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil can be effective for hair loss but should be avoided in people with certain heart conditions and severe liver problems.
22 citations
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February 2008 in “Journal of Neurochemistry” Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
3 citations
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June 2018 in “Bioorganic & medicinal chemistry” Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
January 2020 in “Korean journal of ophthalmology/Korean Journal of Ophthalmology” Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.