6 citations
,
September 1988 in “Drug intelligence & clinical pharmacy” Minoxidil caused a severe rash in a patient, which improved after stopping the drug.
80 citations
,
November 1975 in “Acta dermato-venereologica” Large doses of glucocorticoids are not suitable for general use in treating severe alopecia areata due to inconsistent results and risks.
Minoxidil can cause hair growth as a side effect.
60 citations
,
June 1997 in “Drugs & Aging” Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.
34 citations
,
March 2007 in “Biochemical and Biophysical Research Communications” Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.
1 citations
,
May 2025 in “Archives of Dermatological Research” January 2025 in “Reactions Weekly” November 2024 in “Reactions Weekly” May 2023 in “Reactions Weekly” May 2019 in “Clinica chimica acta” The study developed methods to measure biomarkers in mice and found differences in hormone levels linked to gut microbiota diversity and stress response.
2 citations
,
January 2022 in “Skin Pharmacology and Physiology” Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
6 citations
,
January 1977 in “PubMed” Minoxidil effectively lowers severe high blood pressure long-term but isn't for routine use.
35 citations
,
July 1981 in “Clinical Pharmacology & Therapeutics” Minoxidil can cause dangerous fluid buildup around the heart.
8 citations
,
June 2023 in “European Journal of Endocrinology” The inhibitor affects androgen metabolism but not ovarian function.
34 citations
,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
March 2023 in “Reactions Weekly” 2 citations
,
January 1986 in “PubMed” Spironolactone improved symptoms in women with hormonal imbalances and had few side effects.
3 citations
,
August 2018 in “Therapeutics and Clinical Risk Management” Corticosteroid therapy for alopecia areata can cause severe hip bone damage.
October 2025 in “Journal of the Endocrine Society” Careful dosing and monitoring are crucial to prevent adrenal insufficiency when using ketoconazole for Cushing's disease.
Minoxidil sulfate, delivered through iontophoresis, can be used to treat hair loss.
109 citations
,
July 1984 in “Circulation” Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.
16 citations
,
January 2018 in “International Journal of Trichology” Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.
1 citations
,
April 1987 in “American Journal of Nursing” Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
3 citations
,
August 2015 in “Clinical and Experimental Obstetrics & Gynecology” Minoxidil is the only drug proven to improve female hair loss, and dextroamphetamine sulfate may be a new treatment for certain types of hair loss.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.
47 citations
,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
1 citations
,
March 2017 in “Al-maǧallaẗ al-’irāqiyyaẗ li-l-’ulūm al-ṣaydalāniyyaẗ/Iraqi journal of pharmaceutical sciences” Nutrient antioxidants helped reduce prednisolone dosage and improved hair growth in alopecia areata patients.
11 citations
,
May 2010 in “Journal of the South African Veterinary Association” Mycophenolate mofetil helped reduce steroid use in treating a dog's autoimmune skin disease.
28 citations
,
January 1996 in “Skin Pharmacology and Physiology” Minoxidil boosts hair cell growth, while cyclosporin does not.
9 citations
,
December 1958 in “Journal of Investigative Dermatology”