June 2024 in “Research Square (Research Square)” Increased cell death and reduced cell growth in hair follicles contribute to baldness.
January 2011 in “Reactions Weekly” Long-term use of minoxidil may cause hair follicles to transform into noticeable terminal hairs, leading to trichostasis spinulosa.
4 citations
,
April 2016 in “Experimental Dermatology” AGA causes hair loss through follicle miniaturization and hair cycle changes; regrowth depends on anagen initiation in kenogen follicles.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
August 2023 in “Journal of analytical & pharmaceutical research” Microneedle-assisted therapy with human basic fibroblast growth factor significantly regrew hair in patients with hair loss.
149 citations
,
July 2017 in “PLoS Biology” Hair follicle patterns form through a mix of self-organization and signaling interactions.
21 citations
,
March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
6 citations
,
July 2007 in “Aesthetic Surgery Journal” The document concludes that using autologous follicular unit implantation is a successful method to correct hairline deformities after facial rejuvenation.
170 citations
,
January 2010 in “animal” Hair follicle growth and fiber production in animals are influenced by chemical signals, proteins, pigmentation, genetics, and nutrients.
4 citations
,
August 2018 in “Journal of Cosmetic Dermatology” Actual harvested hair follicles were fewer and differed in type from estimated, with older patients and those with multiple transplants needing more careful planning.
98 citations
,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
7 citations
,
November 2017 in “Plastic and reconstructive surgery. Global open” FUE and SMP together can effectively treat hair loss, needing fewer procedures.
4 citations
,
April 2018 in “Biotechnology Letters” Human growth factor 20 can boost mouse whisker growth.
5 citations
,
January 2019 in “Methods in molecular biology” Multiphoton microscopy can effectively image live cells in cornea, skin, and hair follicles over time.
71 citations
,
May 1996 in “Journal of Investigative Dermatology” Ornithine decarboxylase is crucial for hair growth regulation in mice.
September 2025 in “Digital Commons - RU (Rockefeller University)” FOXC1 is essential for keeping hair follicle stem cells inactive and maintaining their environment for healthy hair growth.
82 citations
,
May 2004 in “British Journal of Dermatology” Stem cells are present in plucked hair follicles and can be maintained in culture.
January 2000 in “Europe PMC (PubMed Central)” Hair bulb cells can create skin-like tissues for potential skin repair.
July 2012 in “Medical Hypotheses” Artemis dysfunction might cause hair loss through telomere shortening.
71 citations
,
June 1993 in “Journal of Investigative Dermatology”
22 citations
,
February 2002 in “Journal of theoretical biology” The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
October 2025 in “Journal of Investigative Dermatology” Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.
78 citations
,
October 2012 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
20 citations
,
August 2014 in “Therapeutic delivery” The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.
January 2022 in “Journal of St. Marianna University” Substances from human hair cells can affect hair loss-related genes, potentially leading to new treatments for baldness.
42 citations
,
December 1990 in “The Journal of Dermatologic Surgery and Oncology” The study found that horizontal sections of scalp biopsies are better for analyzing hair loss, showing fewer hairs and more fine hairs in balding areas.
1 citations
,
April 1998 in “PubMed”
December 2022 in “Scientific Reports” Stem cells from whiskers can be transplanted to stimulate hair growth.