research COVID-19: The question of genetic diversity and therapeutic intervention approaches
COVID-19 treatments and vaccines face challenges due to genetic differences in people and the virus.
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480-510 / 1000+ resultsresearch Emergence of the natural history of Myhre syndrome: 47 patients evaluated in the Massachusetts General Hospital Myhre Syndrome Clinic (2016–2023)
Myhre syndrome symptoms worsen over time, with specific genetic variants affecting severity.
research Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems
Advanced hydrogels can autonomously deliver drugs to treat radiation skin injuries, but challenges remain for clinical use.
research Biomedical applications of organoids in genetic diseases
Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
research Hair regrowth in alopecia areata and re‐pigmentation in vitiligo in response to treatment: Commonalities and differences
Hair regrows faster in alopecia areata than skin re-pigments in vitiligo due to differences in stem cells and treatment effects.
research The sebaceous gland revisited: Friend and adversary
Sebaceous glands help protect and maintain healthy skin and hair.
research Amplicon-based sequencing and co-occurence network analysis reveals notable differences of microbial community structure in healthy and dandruff scalps
Dandruff scalps have unstable microbes, more Malassezia, less Cutibacterium, and targeting Lactobacillus may help.
research Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail—Implications for Disease and Regeneration
Wnt signaling is crucial for skin, hair, and nail health and regeneration.
research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research EMT Factors and Metabolic Pathways in Cancer
EMT and metabolic pathways help cancer cells resist treatment and spread.
research A Systematic Scoping Review and Conceptual Analysis of New-Onset Fibromyalgia Manifestations After Non-Hospitalized COVID-19: Empirics, Definitions, Methodologies, Pathophysiology, Mapping of Literature, and Knowledge Gaps
New-onset fibromyalgia after COVID-19 is poorly understood and needs more research.
research Prolactin: A Mammalian Stress Hormone and Its Role in Cutaneous Pathophysiology
Prolactin affects skin health and may lead to new treatments for skin and hair issues.
research The Skin Microbiome: Current Landscape and Future Opportunities
The skin microbiome is crucial for skin health, and more research is needed to explore its role and potential treatments.
research Skin Structure, Physiology, and Pathology in Topical and Transdermal Drug Delivery
Improving drug delivery through the skin requires understanding skin and using enhancers.
research Types of Human Stem Cells and Their Therapeutic Applications
Stem cells can be reprogrammed for various treatments, but safety and expansion challenges remain.
research Referee report. For: Case Report: Extensive digital gangrene as a primary manifestation of late-onset systemic lupus erythematosus [version 2; peer review: 2 approved]
Digital gangrene can be an unusual first sign of late-onset lupus.
research Hair Follicles as a Critical Model for Monitoring the Circadian Clock
Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
research Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases
More precise, personalized therapies are needed for autoimmune diseases.
research A review for cell-based screening methods in drug discovery
Cell-based screening methods are useful and cost-effective for drug discovery but have pros and cons.
research Mechanism of action and promising clinical application of melatonin from a dermatological perspective
Melatonin may help treat skin conditions.
research Enzymes
Enzymes play crucial roles in metabolism, health, and disease management.
research Highlights from the Literature
Apoptosis, not oxidative stress, is linked to aging in mice with mtDNA mutations.
research Cell death by cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Coordination of force-generating actin-based modules stabilizes and remodels membranes in vivo
Actin filaments help stabilize and reshape cell membranes.
research Transcriptomic Analysis of Skin Tissue Reveals Molecular Mechanisms of Thermal Adaptation in Cold-Exposed Lambs
Hulunbuir lambs adapt better to cold than Hu lambs, showing more wool growth and thicker skin.
research The Who’s, What’s, and “Y”s: Y Sex Chromosome Loss and Methylation for Analysis in Male Aging and Mortality and Forensic Science Applications
Understanding the Y chromosome is key to male health, aging, and developing diagnostic tools.
research Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants
Natural antioxidants like flavonoids and resveratrol may help prevent low testosterone in aging men.
research Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice
A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
research MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation
Tiny particles from stem cells can help protect ear cells from antibiotic damage by helping cells remove damaged parts.
research Central nervous system involvement in autoimmune polyglandular syndrome
Autoimmune polyglandular syndrome can cause temporary brain issues that may improve on their own.