June 2025 in “Cell Metabolism” Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
March 2024 in “International journal of molecular sciences” Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
295 citations
,
March 2016 in “Life Sciences” Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.
66 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.
19 citations
,
July 2018 in “Mechanisms of Ageing and Development” Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
16 citations
,
November 2021 in “Antioxidants” Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
3 citations
,
August 2020 in “Cutaneous and Ocular Toxicology” ATP helps prevent skin damage from vandetanib by reducing stress.
2 citations
,
November 2025 in “Nutrition Journal” Probiotic supplements may help reduce inflammation and oxidative stress in women with PCOS.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” Red light exposure can slow aging in mice by improving fat metabolism.
January 2023 in “Journal of Ravishankar University” Hair loss can be caused by stress, aging, and harmful substances that create an imbalance in the body's natural processes.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
277 citations
,
February 2013 in “Science Signaling” Mitochondrial reactive oxygen species are essential for skin and hair development.
252 citations
,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
150 citations
,
April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
109 citations
,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
102 citations
,
January 2003 in “Dermatology” Smoking may contribute to hair loss in men.
91 citations
,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
88 citations
,
August 2014 in “PLOS genetics” Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
80 citations
,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
79 citations
,
January 2017 in “Dermatology practical & conceptual” Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.
75 citations
,
January 2014 in “Archiv Der Pharmazie” Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
75 citations
,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
62 citations
,
July 2018 in “Lasers in Medical Science” LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.
56 citations
,
March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
53 citations
,
January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
41 citations
,
June 2024 in “Journal of Cellular and Molecular Medicine” Natural antioxidants may help prevent hair loss by reducing oxidative stress.
36 citations
,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
28 citations
,
August 2015 in “Journal of Drug Targeting” The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
26 citations
,
June 2016 in “Pediatric Dermatology” Premature hair graying in young Turkish adults is more likely if they have stress, a family history of graying, drink alcohol, have chronic diseases, are older, or are taller.
26 citations
,
June 2016 in “Journal of Reproductive Immunology” Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.