8 citations
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February 2017 in “Clinical Drug Investigation” Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.
15 citations
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April 1997 in “Muscle & Nerve” 5 citations
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April 1997 in “Muscle & Nerve” January 2002 in “HAL (Le Centre pour la Communication Scientifique Directe)” The enzyme system in hair follicles is similar to the liver's and is inhibited by certain substances.
March 2016 in “West Indian medical journal” There is no significant link between alopecia areata and the PON1 enzyme polymorphisms studied.
December 2023 in “Toxicology communications” Minoxidil overdose caused severe low blood pressure, but the patient recovered with specific treatments.
January 2026 in “Magazine Portal Bibliotech Digital (Universidad Nacional de Colombia)” Minoxidil and finasteride effectively treat hair loss but may cause side effects; combining them improves results.
98 citations
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August 2004 in “BJU international” Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.
1 citations
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October 2017 in “Food Additives & Contaminants: Part A” A new minoxidil-like substance, triaminodil, was found in an illegal hair growth supplement.
January 2021 in “Journal of The European Academy of Dermatology and Venereology” Men with hair loss who take a certain type of medication may experience fewer COVID-19 symptoms.
13 citations
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January 1997 in “Biochemical Pharmacology” Human liver enzyme DHEA ST helps process minoxidil.
August 2023 in “Journal of Cosmetic Dermatology” Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
November 2023 in “Circulation” Minoxidil can cause a rare but serious condition that leads to fluid buildup around the heart and drug-induced lupus.
3 citations
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February 2019 in “Molecular genetics and metabolism” The combination of tadalafil and finasteride improves urinary symptoms and erectile function in men with enlarged prostates.
September 2023 in “Translational medicine reports” Minoxidil ingestion can raise liver enzyme levels.
January 2020 in “Korean journal of ophthalmology/Korean Journal of Ophthalmology” Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.
27 citations
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April 2008 in “Neuroscience Letters” Olanzapine reduces stress-related anxiety in rats when given acutely.
July 2022 in “International Journal of Contemporary Medicine” Lower Paraoxonase 1 levels in alopecia areata patients suggest antioxidant treatment might help.
48 citations
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June 1988 in “PubMed” Minoxidil sulfate relaxes muscle by increasing potassium flow, making it a unique muscle relaxer.
47 citations
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October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
January 2016 in “Archivio italiano di urologia, andrologia” The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
June 2014 in “Reactions Weekly” Finasteride can cause muscle weakness and eye movement issues, even at low doses.
March 2025 in “Journal of the American Academy of Dermatology” Dutasteride and finasteride do not increase mood disorder risk in men with hair loss.
37 citations
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May 2016 in “JAAD case reports” Oral minoxidil shows promise in treating monilethrix-related hair loss.
April 2023 in “Medicina Clínica (english Edition)” 25 citations
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June 2017 in “Neuropharmacology” Increasing TSPO in the brain reduces anxiety and depression.
49 citations
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October 1994 in “Annals of Oncology” Minoxidil not effective in preventing chemotherapy-induced hair loss.
May 2024 in “Brain disorders” Agmatine may help reduce seizures linked to hormone changes in female rats.
1 citations
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January 1981 in “Elsevier eBooks” Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.
May 2022 in “The Journal of Sexual Medicine” Amoxapine may be effective for treating ejaculatory dysfunction.