research Exploring a biological tissue from atomic to macroscopic scale using synchrotron radiation: example of hair.
Hair has unevenly distributed proteins and lipids, with lipids mainly in the cuticle and proteins in the cortex and medulla.
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300-330 / 1000+ resultsresearch Encapsulation of curcumin into nanoparticles
Encapsulating curcumin in nanoparticles improves its stability, release, and absorption in the body.
research Temperature-dependent phase transition microemulsions for enhanced transdermal delivery of finasteride and silodosin
Menthol-based microemulsions improve skin delivery of finasteride and silodosin.
research Melatonin-Loaded Nanoparticles for Enhanced Antidepressant Effects and HPA Hormone Modulation
Melatonin-loaded nanoparticles improve antidepressant effects and HPA hormone balance better than regular melatonin.
research Niosomes: A Novel Targeted Drug Delivery System
Niosomes are a promising method for delivering drugs directly to targeted areas in the body.
research Design, optimization, and in vitro characterization of fastdissolving tablets of nifedipine using response surface methodology
The study focused on developing fast-dissolving tablets (FDTs) of nifedipine, a poorly water-soluble antihypertensive agent, using a spray-drying approach and response surface methodology for optimization. The optimized tablets demonstrated rapid disintegration in less than 120 seconds, reduced wetting time, and enhanced dissolution profiles. The solubility of nifedipine was significantly improved in ethanol compared to aqueous media. The design of experiments (DoE) models indicated statistically significant effects of formulation variables on the tablets' performance. Solid-state studies confirmed the compatibility of the drug with excipients. Overall, the study successfully developed nifedipine FDTs with improved in vitro performance, suggesting their potential for better oral delivery.
research Cholesterol and Phospholipid-free Multilamellar Niosomes Regulate Transdermal Permeation of a Hydrophobic Agent Potentially Administrated for Treating Diseases in Deep Hair Follicles
Cholesterol- and phospholipid-free niosomes improve deep skin drug delivery.
research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With an Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability
Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
research A reciprocal lattice approach to assessing the luster of hair fibers, based on scattering by periodically deformed cylinders
A new method helps understand hair shine and various products improve hair care.
research Bone‐forming cells with pronounced spread into the third dimension in polymer scaffolds fabricated by two‐photon polymerization
Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.
research Surfactants' Role in Nanovesicles Drug Delivery System
Surfactants in spanlastics improve drug delivery by making nanovesicles more flexible and stable for painless administration through the mouth.
research Noyes-Whitney Dissolution Model-Based pH-Sensitive Slow Release of Paclitaxel (Taxol) from Human Hair-Derived Keratin Microparticle Carriers
Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
research Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases
The microneedle system shows promise for non-invasive brain drug delivery.
research A comprehensive review on invasomal carriers incorporating natural terpenes for augmented transdermal delivery
Invasomes with natural terpenes can improve drug delivery through the skin.
research Design and synthesis of potential nano-carrier for delivery of diphencyprone to hair follicle
research Bridging the organoid translational gap: integrating standardization and micropatterning for drug screening in clinical and pharmaceutical medicine
Standardizing and engineering organoids can improve their use in medicine and drug testing.
research Enzyme‐Instructed Self‐Assembly for Cellular Supramolecular Chemistry
EISA uses enzymes to create precise nanostructures in cells, offering new ways to design adaptive materials and therapies.
research Safety Profile and Efficacy of Biosea® Revive Serum for Hair Growth Through In Vitro Assessment and Clinical Evaluation
Biosea® Revive Serum is safe and effective for improving hair growth and health.
research Cocktail Cell‐Reprogrammed Hydrogel Microspheres Achieving Scarless Hair Follicle Regeneration
New microspheres help heal skin wounds and regrow hair without scarring.
research Structural characterization and dissolution profile of mycophenolic acid cocrystals
The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.
research Triggering of drug release of particles in hair follicles
New method uses hair follicles to deliver drugs deep into the skin.
research Optimum Preparation Conditions for Highly Individualized Chitin Nanofibers Using Ultrasonic Generator
Using ultrasonication at 45 kHz for 30 minutes is an efficient, low-cost way to produce high-quality chitin nanofibers from crab shells.
research Newly born mesenchymal cells disperse through a rapid mechanosensitive migration
Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
research Nanocrystals of medium soluble actives—Novel concept for improved dermal delivery and production strategy
Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
research Core-shell and core-amphiphilic branched shell nanocarriers based on biodegradable hyperbranched polymers, as potential drug delivery systems
The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.
research Potential Multi‐Functional Sprayable Poly(N‐Isopropylacrylamide)/Dextran Hydrogel Dressings With Incorporation of Silver Nanowires
The sprayable hydrogel is safe and effective for wound healing, killing bacteria and reducing oxidation.
research Water distribution in human hair microstructure elucidated by spin contrast variation small-angle neutron scattering
The technique showed that human hair has two main parts, with 68% being rigid and the rest flexible, and water swelling affects its structure.
research Microemulsions as a Surrogate Carrier for Dermal Drug Delivery
Microemulsions can effectively deliver drugs through the skin but require careful ingredient selection to avoid irritation.
research Studies of light scattering from ethnic hair fibers
Different hair types from various ethnic groups affect hair shine due to characteristics like thickness and shape.
research Development and Characterization of Thiolated Cyclodextrin-Based Nanoparticles for Topical Delivery of Minoxidil
Thiolated cyclodextrin-based nanoparticles effectively deliver Minoxidil for scalp treatment without causing skin irritation.