EGF and FGF signaling stops hair follicle development in mice.
44 citations
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March 2012 in “Molecular Carcinogenesis” Keratin 15 cells from hair follicles help develop and maintain skin tumors in mice.
77 citations
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April 1968 in “Development” Excess vitamin A can cause hair follicles to change into gland-like structures.
28 citations
,
February 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b helps skin cells and hair grow.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.
April 2010 in “Cancer Research” CDK4 levels affect the number of hair follicle stem cells in mice.
21 citations
,
June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
79 citations
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August 1998 in “The Journal of Cell Biology” Keratin 16 delays skin maturation and affects skin and hair development in mice.
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
25 citations
,
October 1984 in “Journal of Clinical Investigation” The model using human skin on mice helps study human sebaceous glands.
49 citations
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October 1989 in “Genomics” Type I keratin genes are closely linked to the rex locus on mouse chromosome 11, affecting hair development.
82 citations
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May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
3 citations
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
81 citations
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September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
6 citations
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August 1975 in “Journal of Endocrinology” Cortisol and corticosterone thin mouse skin and regress hair follicles, while testosterone promotes skin and hair development.
7 citations
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November 2016 in “Oncotarget” UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
4 citations
,
June 2015 in “Connective tissue research” The research found changes in gene expression related to cell death in mouse skin that help understand hair follicle development and skin health.
48 citations
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March 2010 in “PloS one” C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
25 citations
,
September 1995 in “Biochemistry and Cell Biology” High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
8 citations
,
January 2013 in “genesis” Zfp157 is active in many mouse tissues during development and in specific adult cells.
128 citations
,
March 1989 in “Experimental Cell Research” Hoxc13 is important for hair and tongue development by controlling hair keratin genes.
63 citations
,
November 2012 in “Journal of Cellular Biochemistry” Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.
16 citations
,
April 2021 in “International Journal of Molecular Sciences” Micro-current stimulation may promote hair growth more effectively than standard treatments.
127 citations
,
April 1999 in “Journal of Investigative Dermatology” Rodent models helped understand psoriasis but none perfectly replicated the disease.
June 2014 in “Biotechnology and Bioprocess Engineering” Injecting lab-grown hair cells into the scalp can regrow hair.
4 citations
,
February 2018 in “Journal of Investigative Dermatology” The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.
Live imaging helps us understand skin immune responses and develop treatments.
16 citations
,
November 1994 in “Developmental Biology” Retinoic acid causes gland formation instead of hair in mouse skin by altering epidermal and dermal interactions.
April 2017 in “Journal of Investigative Dermatology” Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.