236 citations
,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
19 citations
,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
2 citations
,
July 2025 in “Frontiers in Veterinary Science” MicroRNAs and AI can improve cashmere goat hair quality and aid in hair disorder diagnosis.
39 citations
,
March 2009 in “Dermatology Online Journal” Understanding EGFR roles could lead to new hair loss treatments.
11 citations
,
February 2021 in “Biomedicines” Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
February 2026 in “International Journal of Molecular Sciences” Muscarinic acetylcholine receptors in skin cells help regulate and promote hair growth.
December 2025 in “Biomolecules” Targeting protein S-palmitoylation could lead to new skin disease treatments.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
47 citations
,
October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
4 citations
,
March 2024 in “Cells” MiR-23b and miR-133 affect sheep hair growth by targeting specific genes.
1 citations
,
May 2012 in “Hair transplant forum international” Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.
318 citations
,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
March 2025 in “International Journal of Pharmaceutical Research and Applications” A multidisciplinary approach is key to delaying aging and preventing age-related diseases.
354 citations
,
February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
57 citations
,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
Nanotechnology shows promise for better hair loss treatments but needs more research for safety and effectiveness.
178 citations
,
August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
2 citations
,
December 2025 in “Cosmetics” Proper scalp care can improve hair health and delay ageing signs.
June 2026 in “International Journal of Molecular Sciences” Black Ginseng Concentrate may help treat hair loss by improving cell function and reducing stress.
March 2026 in “Trends in Sciences” A mouse model was created to study hair loss similar to humans.
October 2024 in “SPIRE - Sciences Po Institutional REpository” Glypicans help hair follicle stem cells differentiate by interacting with specific receptors, influencing hair growth.
August 2024 in “Quality in Sport” PRP helps with skin, hair, and wound treatments but needs more research for standard use.
January 2016 in “Journal of Materials Chemistry B” Advancements in biomaterials and nanotechnology are improving medical applications like hair growth, bone regeneration, and cancer treatment.
66 citations
,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
April 2023 in “Journal of Investigative Dermatology” The study found that aging hair follicle stem cells change behavior, leading to hair loss, but drugs targeting these cells may help restore hair growth.
32 citations
,
February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
1 citations
,
July 2024 in “International Journal of Molecular Sciences” MicroRNA-181a slows sheep hair growth by targeting GNAI2 and affecting a key growth pathway.