research PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery
PandaOmics uses AI to find new disease treatment targets and biomarkers.
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60-90 / 778 resultsresearch Comparative Study of Some Potential Paracrine Factors Produced by Normal and Androgenetic Alopecia Hair Follicles
Balding hair follicles have less growth-promoting factors and more inhibitory factors, leading to hair loss.
research Proteome Analysis of Human Hair Shaft
Human hair contains many proteins, with some being highly abundant and modified.
research ST14 interacts with TMEFF1 and is a predictor of poor prognosis in ovarian cancer
High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
research Scoparone Induces Expression of Pluripotency Transcription Factors SOX2 and NANOG in Dermal Papilla Cells
Scoparone may help stimulate hair growth by increasing stem cell-related proteins in skin cells.
research Bridging the organoid translational gap: integrating standardization and micropatterning for drug screening in clinical and pharmaceutical medicine
Standardizing and engineering organoids can improve their use in medicine and drug testing.
research Signal integrator function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
Engineered skin tissue is a promising tool for safer cosmetic testing.
research Integration of Colorimetric Sensing Dyes and Multi‐Substrate Arrays for Food Quality and Safety Monitoring: Design, Optimization, and Analysis
Combining advanced sensors with portable devices could enhance on-site food safety monitoring.
research Advances and Challenges in Plant Sterol Research: Fundamentals, Analysis, Applications and Production
Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.
research Precision and Personalized Medicine in Transdermal Drug Delivery Systems: Integrating AI Approaches
AI-enhanced smart patches can personalize drug delivery for better treatment outcomes.
research Comparison of Current International Guidelines for the Management of Alopecia Areata—Comprehensive Review
International guidelines for treating alopecia areata vary, focusing on different treatment options and related health issues.
research SYSTEMATIC REVIEW OF PHARMACOTHERAPY STRATEGIES IN THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA
Biologic agents are effective for severe hidradenitis suppurativa when other treatments fail.
research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study
Botox increased hair count in men with baldness and might work by improving scalp blood flow.
research In Search of Predictive Models for Inhibitors of 5-alpha Reductase 2 Based on the Integration of Bioactivity and Molecular Descriptors Data.
The models can help find better inhibitors for conditions like baldness and prostate disorders.
research AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response
AI improves biomaterial design by making it faster, cheaper, and more effective for personalized medicine.
research The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell size
Cell size controls when stem cells divide.
research IMMUNOLOGICAL AND SOME BIOLOGICAL BIOMARKERS INVESTIGATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
No single biomarker is reliable enough for diagnosing and assessing SLE.
research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging
Curcumin may help reverse aging by targeting specific genes.
research Biological and mechanical influence of three-dimensional microenvironment formed in microwell on multicellular spheroids composed of heterogeneous hair follicle stem cells
3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.
research Sequence-structure based phylogeny of GPCR Class A Rhodopsin receptors
The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Expanding the Clinical and Mutational Spectrum of Recessive AEBP1-Related Classical-Like Ehlers-Danlos Syndrome
The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.
research Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection
Skin organoids can model tuberculosis infection and help test treatments.
research Combined Physicochemical and Transcriptomic Analyses Reveal the Effect of Black Wolfberry Ferment on Alopecia
Black wolfberry ferment may help regrow hair in cases of androgenetic alopecia.
research Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids
Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
research Targeting lymphoid-derived IL-17 signaling to delay skin aging
Blocking IL-17 signaling may reduce skin inflammation and delay aging.
research Generation of trichogenic adipose-derived stem cells by expression of three factors
Scientists made stem cells that can grow hair by adding three specific factors to them.