December 2025 in “Current Issues in Molecular Biology” Cytarabine can cause multiple organ toxicities, especially neurotoxicity, but better research methods are needed to fully understand and predict these effects.
October 2024 in “Dermatologic Surgery” PRP and PRF show promise for hair growth but need more research for consistent and safe use.
February 2026 in “Journal of Thoracic Disease” Long COVID is a big health problem needing more research and better treatments.
January 2025 in “Diagnostics” 3D high-frequency ultrasound can help diagnose skin and hair conditions without invasive biopsies.
309 citations
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June 2001 in “Molecular and Cellular Endocrinology” Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.
248 citations
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August 2015 in “Pharmacological Research” Vaccines are generally safe, but rare autoimmune reactions can occur, often influenced by genetics.
227 citations
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April 2020 in “Cell” More precise, personalized therapies are needed for autoimmune diseases.
107 citations
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March 2014 in “BoneKEy Reports” Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.
85 citations
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March 2008 in “Journal of Cell Science” The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.
81 citations
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February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
74 citations
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February 2011 in “Headache The Journal of Head and Face Pain” Sumatriptan injections, high-flow oxygen, and verapamil effectively treat cluster headaches.
57 citations
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October 2021 in “Journal of ethnopharmacology” Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.
52 citations
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September 2022 in “Viruses” SARS-CoV-2 proteins help the virus avoid the immune system, delaying response and increasing inflammation.
48 citations
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April 2008 in “Human Molecular Genetics” Progerin affects cell shape but not hair or skin in mice.
29 citations
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February 2022 in “Frontiers in Cell and Developmental Biology” Improving CRISPR/Cas systems can make gene editing more efficient and precise.
26 citations
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January 2018 in “Skin appendage disorders” Thallium, mercury, selenium, and colchicine strongly cause hair loss.
26 citations
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February 2016 in “Respiratory Medicine” Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
22 citations
,
March 2023 in “Bioengineering” Stem cell therapies may help improve symptoms and quality of life for people with epidermolysis bullosa.
14 citations
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March 2022 in “Clinical Endocrinology” The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).
13 citations
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January 2024 in “Cadernos de Saúde Pública” Many hospitalized COVID-19 patients still have symptoms like fatigue and hair loss up to a year later, especially older, lower-income individuals with other health issues.
13 citations
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September 2022 in “Frontiers in immunology” Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
12 citations
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June 2023 in “International Journal of Molecular Sciences” Innovative biomaterials show promise in healing chronic diabetic foot ulcers.
10 citations
,
August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
9 citations
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November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
8 citations
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May 2025 in “Pharmaceuticals” In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
8 citations
,
May 2022 in “Orphanet Journal of Rare Diseases” The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.
7 citations
,
July 2023 in “International Journal of Molecular Sciences” Hyaluronic acid reduces cell damage from DMSO in preserved human cells.
7 citations
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December 2021 in “European Respiratory Review” The document concludes that diagnosing and treating Interstitial Pneumonia with Autoimmune Features (IPAF) is challenging, needs a multidisciplinary approach, and further research for better diagnostic criteria and treatments. It also emphasizes regular checks for Connective Tissue Disease symptoms in all patients with Interstitial Lung Disease.
6 citations
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August 2024 in “Viruses” Long COVID is a complex condition with many symptoms and unknowns, needing more research.
6 citations
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February 2022 in “JAAD International” Higher doses of isotretinoin may lead to more hair loss.