16 citations
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May 2000 in “Endocrinology” A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
41 citations
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December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
16 citations
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December 2020 in “PloS one” Researchers found WNT10A to be a key gene in developing goat hair follicles.
21 citations
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June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
Meis2 is essential for touch sensation and nerve function in mice.
3 citations
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January 2022 in “Burns & Trauma” CTHRC1 helps sweat glands recover by rebuilding nearby blood vessels.
76 citations
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June 2018 in “EMBO Reports” YAP and TAZ proteins are necessary for the development of two types of skin cancer.
133 citations
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January 2009 in “Nature” Lgr5 and the vitamin D receptor are key in controlling skin inflammation and tumor risk in mice.
January 2018 in “Bradford Scholars (University of Bradford)” SWI/SNF complexes are crucial for wound healing but not for hair growth.
1 citations
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December 2018 in “Journal of cutaneous pathology” Some skin growths with mucin can form hair follicles and resemble skin cancer, but a special stain can help tell them apart.
April 2023 in “Journal of Investigative Dermatology”
3 citations
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April 2014 in “Journal of Dietary Supplements” CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.
July 2025 in “Scientific Reports” Six key genes can predict bladder cancer outcomes and may serve as prognostic biomarkers.
1 citations
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November 2022 in “Animals” The research found specific genes and pathways that control fur development and color in young American minks.
May 2019 in “CINECA IRIS Institutial Research Information System (University of Genoa)” MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.
June 2010 in “European Journal of Cancer Supplements” Senescent fibroblasts can help start tumors in normal skin cells.
November 2018 in “Atlas of genetics and cytogenetics in oncology and haematology” WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
1 citations
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February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
January 1999 in “Praxis sociológica” Melanocyte stem cells can become melanoma, resembling human melanoma.
25 citations
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January 2013 in “Journal of Cell Science” Tenascin-C and tenascin-W help control stem cell movement and growth in whisker follicles.
May 2018 in “Cell stem cell” Myoepithelial cells can repair airways after severe injury.
Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
83 citations
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February 1991 in “Development” Fos protein is crucial for cell transition to cornification in keratinized tissues.
March 2026 in “Tissue Engineering and Regenerative Medicine”
202 citations
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August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
101 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
51 citations
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November 2013 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.