August 2023 in “Journal of Cosmetic Dermatology” Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
6 citations
,
August 2024 in “Experimental Dermatology” Irisin can promote hair growth by activating a specific signaling pathway.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Not having enough cystatin M/E protein causes less hair growth and dry skin.
36 citations
,
March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
44 citations
,
July 2012 in “Endocrine Practice” We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
100 citations
,
March 2006 in “Journal of biological chemistry/The Journal of biological chemistry” Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.
April 2024 in “Journal of cosmetic dermatology” Minoxidil is less effective on eyebrows and eyelashes than scalp hair because these areas have lower enzyme activity needed to activate the drug.
9 citations
,
September 2013 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
1 citations
,
June 2021 in “Journal of Cosmetic Dermatology” Enzyme booster SULT1A1 greatly enhances hair regrowth with minoxidil.
Sox13 is a marker for early hair follicle development but not essential for skin and hair growth.
2 citations
,
October 2020 in “Journal of Pharmacology and Experimental Therapeutics” Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.
January 2010 in “Jounal of The Korean Society of cosmetology” Rosemary oil may promote hair growth by enhancing enzyme activities and IGF-1 expression.
18 citations
,
October 2022 in “JCI Insight” Abnormal amino acid metabolism may worsen rosacea symptoms.
49 citations
,
May 1974 in “Biochimica et Biophysica Acta (BBA) - Protein Structure” Transamidases are present in the epidermis but their exact role is unclear.
10 citations
,
November 2018 in “Genetics in medicine” Lack of cystatin M/E causes thin hair and dry skin.
10 citations
,
October 2018 in “Plant Biotechnology” Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.
September 2022 in “Research Square (Research Square)” 5% topical minoxidil improves hair density and quality in monilethrix patients.
2 citations
,
November 2022 in “Skin research and technology” 5% topical minoxidil improves hair density and quality in monilethrix patients.
4 citations
,
May 2019 in “PubMed” Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.
4 citations
,
August 2010 in “Acta Biologica Hungarica” New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
December 2023 in “Research Square (Research Square)” 12-Methoxy carnosic acid from rosemary might be a good natural treatment for hair loss.
8 citations
,
September 1987 in “Acta Dermato Venereologica” Recessive X-linked ichthyosis involves a less efficient enzyme in hair follicles, suggesting two distinct enzymes.
January 2025 in “Journal of Materials Chemistry B” The microneedle patch with CuxO nanozymes effectively promotes hair growth for treating hair loss.
June 2025 in “Turkish Journal of Dermatology” Acne patients have lower enzyme activity, suggesting oxidative stress may contribute to acne.
1 citations
,
March 2022 in “Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy” A new, quick method detects minoxidil using silver nanoparticles.
1 citations
,
September 2001 in “PubMed” ONO-3403 effectively reduces mouse skin tumor growth without side effects.
22 citations
,
October 2004 in “Journal of Investigative Dermatology” The gene causing hair loss and heart issues in rough coat mice is still unknown.
29 citations
,
January 2020 in “BioMed Research International” Sinapic acid may help fight obesity and promote hair growth.
93 citations
,
September 2014 in “Diabetes” Lack of 5α-Reductase type 1 can lead to insulin resistance and liver problems.
64 citations
,
January 2009 in “Gynecological Endocrinology” Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.