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A new keratin 6 type in mice explains why some mice without certain keratin genes still have normal hair and nails.

Hair and nail proteins, mainly keratins, are crucial for structure and can indicate health issues.

Defective repair processes may cause immune activation and inflammation in psoriatic disease.

Mutations in the KLHL24 gene cause skin blistering in epidermolysis bullosa simplex.

Elkonyxis, a rare nail condition, improved when patients stopped their nail-picking habits.

FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

New RIPK4 gene mutations were found to cause a type of skin and limb birth defect.

Skin problems are very common in people with end-stage kidney disease.

Genetic defects in the Wnt/PCP pathway may cause congenital yellow nail syndrome.

HOXC13 is essential for hair and nail development by regulating Foxn1.

Experts discussed hair care, genetic hair defects, hair loss treatments, nail surgery, lupus treatments, skin infections, and cosmetic allergies.

Malabsorption can cause skin issues like pigmentation changes and hair loss, which improve with treatment.

Alopecia areata can cause spotty white areas on nails.

Nail abnormalities in children can indicate deeper health issues.

Clouston syndrome causes issues with teeth, hair, nails, and skin, and has no cure, but recognition has improved.

A new side effect of aromatic retinoid treatment is soft nails.

A child with ectodermal dysplasia-syndactyly syndrome has a new mutation in the NECTIN4 gene.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

Hoxc13 gene is essential for hair, nail, and papilla development.

A wide range of proteins are integrated into the skin's protective layer.

GABEB is a less severe skin condition caused by a gene mutation affecting collagen, leading to blisters and other symptoms.

Abnormal keratin expression in mice causes severe oral issues, affecting feeding.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

Pigmentary mosaicism causes skin color changes and can affect multiple body systems, but has no cure.

A girl with a rare genetic condition affecting hair and nails also developed a common type of hair loss, suggesting a possible genetic link.

Monilethrix is linked to a gene cluster on chromosome 12.

Using special RNA to target a mutant gene fixed hair problems in mice.

Valproic acid can rarely cause reversible nail discoloration.

Biotin and acetazolamide improved hair and nail growth, mental function, and reduced headaches in a child with autism.