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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

A comprehensive, personalized approach is needed for treating female pattern hair loss and obesity, involving multiple medical disciplines and lifestyle changes.

Oral isotretinoína effectively stabilizes frontal fibrosing alopecia.

Long-term treatment with buprenorphine/naloxone for opioid addiction may lead to secondary adrenal insufficiency.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Finasteride reduces opioid use and withdrawal symptoms in animals.

Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.

Finasteride may help reduce opioid use.

Ethanol withdrawal reduces the brain's response to certain calming steroids, making seizures harder to control.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Allopregnanolone may help prevent nicotine withdrawal symptoms.

Upadacitinib may effectively treat twenty-nail dystrophy without causing pain.

Adjusting neurosteroid levels may help reduce alcohol withdrawal symptoms.

Neurosteroids may help metyrapone reduce cocaine addiction.

GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.

Bupropion SR may help treat trichotillomania.

Oral difelikefalin significantly reduces itch in notalgia paresthetica.

In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.

Allopregnanolone and opioids together reduce stress hormone responses during pregnancy.

Stopping alcohol after long-term use causes anxiety and changes brain chemicals.

Activating liver X receptors can reduce fibrosis by stopping certain immune cells from releasing harmful proteins.

Raltitrexed conjugates are less potent than the free drug but more effective at high concentrations.

μ-opiate receptors in skin cells may affect skin health and healing.

LGD1069 effectively prevents breast tumors in mice without toxicity.

Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.

Anionic squarticles can effectively counteract amitriptyline overdose, improving survival rates.

Proxalutamide helps COVID-19 patients get rid of the virus faster and recover quicker.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

An HIV patient's complete hair loss was reversed after switching from lopinavir/ritonavir to nelfinavir.