research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
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research Neurosteroids on the Epilepsy Chessboard—Keeping Seizures in Check
Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.
research Avaliação de respostas defensivas associadas ao pânico em ratas: perfil da ativação serotonérgica no núcleo dorsal da rafe e substância cinzenta periaquedutal
Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.
research How Does Altered Metabolism Lead to Seizure Control? Partially Filling the Knowledge Gap
Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
research Effects of mitotane treatment on human steroid metabolism: implications for patient management
Mitotane changes steroid breakdown, affecting cortisol availability.
research Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review)
The link between anabolic agents and colorectal cancer risk is unclear.
research Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation
Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
research Finasteride inhibited brain dopaminergic system and open-field behaviors in adolescent male rats
Finasteride affects young male rats' brain function and behavior negatively.
research Testicular Steroidogenesis
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Distinctive Acne Entities
Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.
research Anabolic-androgenic steroids and cardiovascular risk
Using steroids can increase the risk of heart problems.
research Drug-induced acne
Some medications can cause acne, and stopping these drugs is the main treatment.
research Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Reporting on Adverse Clinical Events
Different medications can cause serious side effects in some people.
research Finasteride induced depression: a prospective study
Finasteride may cause slight depression and anxiety.
research Pharmacology of anabolic steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Hormonal Treatment Strategies Tailored to Non-Binary Transgender Individuals
Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.
research Adverse health effects of androgen use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Beneficios y riesgos de los implantes de testosterona en mujeres: revisión sistemática de la literatura
The risks of testosterone implants in women outweigh the benefits.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Health consequences of anabolic steroids: a sexual-medicine perspective
Anabolic steroid abuse can cause sexual, fertility, and health problems.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research The acne hormones
Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.
research Testosterone and doping control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Post-finasteride syndrome: An emerging clinical problem
Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
research Gender Differences in Skin Aging and the Changing Profile of the Sex Hormones with Age
The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.
research Sexual dimorphism following in vitro ischemia in the response to neurosteroids and mechanisms of injury
Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.
research LC-MS/MS improves screening towards 21-hydroxylase deficiency
LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
research The association of medications and supplements with human male reproductive health: a systematic review
Some medications and supplements can affect male fertility, with some improving and others harming sperm quality.