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GlossaryNeocollagenesis

process of forming new collagen in skin tissue

Neocollagenesis is the process by which new collagen is formed in the skin. This can occur naturally as part of the body's healing process or be stimulated through treatments like microneedling, laser therapy, or certain injectables. For professionals, understanding neocollagenesis is crucial for developing and applying anti-aging and skin-rejuvenation therapies.

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research Radiofrequency treatment induces fibroblast growth factor 2 expression and subsequently promotes neocollagenesis and neoangiogenesis in the skin tissue

32 citations , May 2017 in “Lasers in medical science”

Radiofrequency treatment helps rejuvenate skin by boosting collagen and blood vessel growth.

Correction of Wrinkles, Peau d’Orange, and Thin Dermis of the Face by Neocollagenesis Using Novel Collagen Stimulating Slurry Protocol

research Correction of Rhytides, Peau d’Orange, and Thin Dermis of the Face by Neocollagenesis Using Novel Collagen Stimulating Slurry Protocol

3 citations , June 2017 in “Aesthetic plastic surgery”

The new facial treatment improved wrinkles and skin thickness, with most patients seeing results within a month, despite some temporary swelling and bruising.

research Radiofrequency Microneedling: A Comprehensive and Critical Review

28 citations , February 2021 in “Dermatologic Surgery”

Radiofrequency microneedling is an effective and safe treatment for various skin conditions and works well with other treatments and on darker skin.

research EFFECTIVENESS OF PLASMOTHERAPY IN VARIOUS NOSOLOGIES

2 citations , July 2023 in “Vrach”

PRP therapy is effective and safe for treating various diseases.

research The use of platelet-rich plasma in dermatology

January 2026 in “Forum Dermatologicum”

Platelet-rich plasma helps improve skin and hair conditions.

research Phenol in dermatology: updated evidence on efficacy and safety

August 2025 in “Anais Brasileiros de Dermatologia”

Phenol is effective for skin treatments but poses serious health risks and must be used cautiously by trained doctors.

Fractional Microneedle Radiofrequency: Mechanism of Action and Assessment of Safety, Effectiveness in Treatment, and Possible Side Effects Based on a Review of Scientific Literature

research Fractional microneedle radiofrequency - mechanism of action and assessment of safety, effectiveness in the treatment, and possible side effects based on a review of scientific literature

July 2023 in “Journal of Education, Health and Sport”

Fractional microneedle radiofrequency is a safe and effective skin treatment with minimal serious side effects.

research Combination Therapy with Injectable Platelet Rich Fibrin (PRF) and Polydioxanone (PDO) Threads in Treatment of Male Pattern Baldness: A Novel Approach

January 2021 in “Hair therapy & transplantation”

Combining PRF and PDO threads shows promise in treating male pattern baldness.

research Nonablative cutaneous remodeling using radiofrequency devices

198 citations , September 2007 in “Clinics in Dermatology”

Radiofrequency devices effectively tighten skin without surgery.

research Microneedling: A means of collagen induction therapy

4 citations , July 2021 in “Journal of dermatology & dermatologic surgery”

Microneedling is a simple, affordable treatment that helps with scars, wrinkles, stretch marks, and hair growth by boosting collagen.

research Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis

September 2017

Type XVII collagen helps control skin cell growth and rejuvenates skin.

research Type XVII collagen coordinates proliferation in the interfollicular epidermis

124 citations , July 2017 in “eLife”

Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.

research Targeting the stem cell niche: role of collagen XVII in skin aging and wound repair

9 citations , January 2022 in “Theranostics”

Collagen XVII is important for skin aging and wound healing.

research Decision letter: Type XVII collagen coordinates proliferation in the interfollicular epidermis

April 2017

Type XVII collagen may help prevent skin aging.

research 0847 The addition of collagen scaffolds to human cell therapy to modify skin identity

July 2025 in “Journal of Investigative Dermatology”

Collagen scaffolds in cell therapy can transform skin to be more resilient and pressure-responsive.

research Expression of Type II Collagen at the Middle Stages of Chick Embryonic and Human Fetal Skin Development

11 citations , June 1994 in “Journal of Investigative Dermatology”

research Collagen-type synthesis in human-hair papilla cells in culture

28 citations , April 1988 in “Archives of Dermatological Research”

research Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis

June 2017

Type XVII collagen helps control skin cell growth and may have anti-aging effects.

research Localization of Type I Human Skin Collagenase in Developing Embryonic and Fetal Skin

22 citations , June 1994 in “Journal of Investigative Dermatology”

research Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin

1 citations , December 2025 in “International Journal of Molecular Sciences”

Atelocollagen boosts collagen production and improves skin elasticity in aged skin.

research 090 Reactive lipids from the secretome of senescent fibroblasts modify the extracellular matrix with functional consequences for resident cells

July 2024 in “Journal of Investigative Dermatology”

Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.

Effects of a New Recombinant Human Collagen on Skin Aging

research Collagen supplementation and regenerative health: advances in biomarker detection and smart material integration

December 2025 in “Frontiers in Nutrition”

Collagen supplements may improve skin, joints, and recovery, especially with added nutrients.