83 citations
,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
68 citations
,
August 2014 in “Stem Cells Translational Medicine” Dermal papilla cells help wounds heal better and can potentially grow new hair.
62 citations
,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
61 citations
,
October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
37 citations
,
June 2017 in “Journal of Investigative Dermatology” Blocking a protein called CXXC5 with a specific peptide can stimulate hair regrowth and new hair growth in wounds.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
8 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
April 2016 in “Journal of Investigative Dermatology” Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.
2 citations
,
January 2013 in “Hair therapy & transplantation” Hair transplants can be a treatment for scarring hair loss if there's good blood flow and no active disease.
36 citations
,
July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
2 citations
,
December 2022 in “Pharmaceutics” The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.
1 citations
,
April 2020 in “European Journal of Dermatology” Apremilast showed mixed results for hair regrowth in alopecia areata.
2 citations
,
April 2022 in “Research Square (Research Square)” Activating PKM2 and Wnt/β-catenin signaling together can potentially enhance hair growth and could be a treatment for hair loss.
13 citations
,
November 2022 in “BMB Reports” Wnt/β-catenin activators can help regrow hair lost due to diabetes.
2 citations
,
May 2018 in “Journal of Investigative Dermatology” Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.
October 2015 in “CRC Press eBooks” Hair cloning for hair loss is not yet a practical solution.
21 citations
,
January 2018 in “The Korean Journal of Physiology and Pharmacology” Modified stem cells from umbilical cord blood can make hair grow faster.
7 citations
,
May 2023 in “Macromolecular Bioscience” Macromolecules show promise for future hair loss treatments.
January 2022 in “Social Science Research Network” Pyruvate Kinase M2 helps hair grow by linking energy production and a key hair growth pathway.
4 citations
,
January 1996 in “British journal of dermatology/British journal of dermatology, Supplement” Mexican hairless dogs can help test new skin treatments.
53 citations
,
April 2021 in “Cell Host & Microbe” Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
37 citations
,
February 2019 in “Experimental Dermatology” Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.
11 citations
,
November 2015 in “Experimental Dermatology” The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
4 citations
,
October 2021 in “Journal of Cellular and Molecular Medicine” White blood cells and their traps can slow down the process of new hair growth after a wound.
June 2020 in “Journal of Investigative Dermatology” Certain bacteria can enhance skin regeneration.
18 citations
,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
January 2020 in “Social Science Research Network” Skin bacteria help in skin regeneration and wound healing, with a specific signal called IL-1β playing a crucial role.
April 2018 in “Journal of Investigative Dermatology” DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.
359 citations
,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
9 citations
,
January 1998 in “Studia Anglica Posnaniensia: international review of English Studies” Wound-induced hair growth may help study regeneration and aging, but it's unclear if this ability decreases with age.