28 citations
,
January 2018 in “Biochemical Society Transactions” Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
28 citations
,
July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
28 citations
,
February 2012 in “PLoS ONE” A PKP1 gene mutation causes skin fragility and hair loss in Chesapeake Bay retriever puppies.
27 citations
,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
27 citations
,
March 2018 in “Biomaterials” Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
27 citations
,
April 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
27 citations
,
August 2015 in “Journal of Investigative Dermatology” The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.
26 citations
,
March 2018 in “Dermatology and Therapy” EPC-CM can reduce skin aging signs by boosting the skin's defense system.
25 citations
,
January 2019 in “Annals of Dermatology” Blocking the NOTCH pathway can prevent fibrosis in systemic sclerosis.
24 citations
,
June 2018 in “Reviews in endocrine and metabolic disorders” Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
23 citations
,
June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
23 citations
,
December 2013 in “Regenerative Medicine” Hair follicle culture helps develop new treatments for hair loss.
22 citations
,
November 2008 in “International Journal of Dermatology” A mix of 5-aminolevulinic acid and iron ion can speed up hair growth.
19 citations
,
February 2017 in “Journal of radiation research” High-dose radiation speeds up aging in skin stem cells.
19 citations
,
March 2011 in “Cutaneous and Ocular Toxicology” Some chemicals absorbed through the skin can cause serious health problems.
16 citations
,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
15 citations
,
February 2011 in “Journal of Tissue Engineering and Regenerative Medicine” The best method for transplanting skin cells to regenerate hair follicles is the Hemi-vascularized sandwich method, as it produces more mature follicles and promotes hair growth.
15 citations
,
May 2013 in “American Journal of Medical Genetics - Part A” People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.
14 citations
,
May 2021 in “Marine Drugs” PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
13 citations
,
March 2021 in “British Journal of Pharmacology” KY19382 helps regrow hair and create new hair follicles.
13 citations
,
January 2021 in “Scientific Reports” Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
11 citations
,
May 2011 in “World Journal of Pediatrics” The document emphasizes the importance of correctly identifying and classifying genetic hair disorders to help diagnose related health conditions.
10 citations
,
May 2024 in “npj Regenerative Medicine” Umbilical cord cells may help delay skin aging.
10 citations
,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
10 citations
,
June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
9 citations
,
October 2017 in “Archivos Argentinos de Pediatria” Alopecia areata needs new treatments targeting autoimmune processes due to its emotional impact and variable treatment responses.
9 citations
,
May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
9 citations
,
March 2011 in “Oxidative stress and disease” Some herbal treatments are effective for skin disorders, but more research and regulation are needed.
6 citations
,
September 2021 in “Experimental Brain Research” Rats have different touch receptors in their paws that help with movement and handling objects.
5 citations
,
October 2020 in “Experimental dermatology” A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.