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Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

Stem cell therapy shows promise for treating skin disorders.

People with hair loss conditions often have more mental health issues like depression and anxiety compared to those without hair loss.

Nanoparticles can make cosmetics more effective but have challenges like cost and safety.

Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.

Ixekizumab has known and some unexpected side effects.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Testosterone therapy is effective and safe for women with low sexual desire, but it's hard to access.

iPSCs help understand and treat neurodevelopmental disorders.

A woman with anorexia nervosa improved after treatment for pellagra, reminding doctors to check for this deficiency in patients with eating disorders.

Gene expression in hair follicles can help diagnose methamphetamine use disorder.

Depression and skin autoimmune diseases are linked, needing combined care for better treatment.

Adrenal disorders often cause high blood pressure in young people.

HHV-6 reactivation may be linked to psychiatric disorders and can improve with antiviral treatment.

PCOS may increase the risk of mental health issues like depression and anxiety.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.

Finasteride, dutasteride, and silodosin have the highest risk for causing sexual dysfunction.

Purpura fulminans can signal underlying autoimmune disorders, not just infections.

Girls with Autism Spectrum Disorder may show different symptoms than boys, leading to missed or delayed diagnoses.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.