387 citations
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November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
66 citations
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December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
27 citations
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January 2006 in “Colloids and Surfaces B: Biointerfaces” Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
January 2014 in “Institutional Repositories DataBase (IRDB)” Fibroblast spheres can form stem cells, but marker distribution needs more study.
13 citations
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February 2024 in “World Journal of Stem Cells” New markers help understand and use hair follicle stem cells for regeneration.
33 citations
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March 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
12 citations
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November 2007 in “Journal of Investigative Dermatology” CD200 is not a reliable marker for identifying stem cells in all skin types.
47 citations
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September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
80 citations
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May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
April 2018 in “Journal of Investigative Dermatology” Key signals for hair follicle formation were identified.
173 citations
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January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
64 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
3 citations
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July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model” Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.
December 2004 in “Reproduction Fertility and Development” Porcine hair follicles are useful for studying keratinocyte function, with galectin-1 as a potential stem cell marker.
74 citations
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October 2023 in “Nature Reviews Molecular Cell Biology”
99 citations
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January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
August 2013 in “International Wound Journal” Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
384 citations
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June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
561 citations
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April 2003 in “Journal of Investigative Dermatology” CD34 is a marker for isolating stem-like cells in mouse hair follicles.
October 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Activating telomerase can boost hair follicle stem cell growth and hair production.
3 citations
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January 2020
499 citations
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September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
6 citations
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May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.
March 2024 in “Tissue and cell/Tissue & cell” Telomerase-positive cells are mainly in the bulb matrix and outer root sheath of hair follicles.
November 2025 in “Journal of Investigative Dermatology” Hair follicle stem cells help maintain skin health after injury.
949 citations
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January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
14 citations
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June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
36 citations
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April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.